The regulation of euchromatin and heterochromatin by histones in yeast
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Pygopus has been discovered as a fundamental Wnt signaling component in Drosophila. The mouse genome encodes two Pygopus homologs, Pygo1 and Pygo2. They serve as context-dependent beta-catenin coactivators, with Pygo2 playing the more important role. All P ...
Since the invention of optical fiber cable data transmission using light has become ubiquitous in the past years. Nonlinear optical effects, which are hardly noticed in our daily life, have become crucial and highly influential for the design and performan ...
Optical fiber materials with broad-band gain in the visible or in the telecommunication window are of great interest for optical communication or the biomedical domain in order to built integrated tunable lasers, amplifiers, ultra-short pulse lasers, or br ...
Eukaryotic DNA is organized in the form of chromatin whose basic unit is the nucleosome. The four core histones forming the nucleosome, H2A, H2B, H3 and H4 can be highly post-translationally modified, especially on their N-terminal tail protruding from the ...
The demand for capacity is growing exponentially with about 40-60% per year passing the installed network capacity. For the last two decades the transmission capacity per fiber has increased by more than three orders of magnitude: Single channel (wavelengt ...
The real remoteness of a distributed optical fiber sensor based on Brillouin optical time-domain analysis is considerably extended in this paper using seeded second-order Raman amplification and optical pulse coding. The presented analysis and the experime ...
The impact of Raman amplification and Simplex coding is studied in combination with differential pulse-width pair Brillouin optical time-domain analysis (DPP-BOTDA) to achieve sub-meter spatial resolution over very long sensing distances. An optimization o ...
It is well established that chromatin is a destination for signal transduction, affecting many DNA-templated processes. Histone proteins in particular are extensively post-translationally modified. We are interested in how the complex repertoire of histone ...
Modulation instability (MI) as the main limit to the sensing distance of distributed fiber sensors is thoroughly investigated in this thesis in order to obtain a model for predicting its characteristics and alleviating its effects. Starting from Maxwell's ...
In this paper we perform an optimization of Brillouin optical time-domain analysis (BOTDA) sensors for achieving high resolution over long sensing ranges using distributed Raman amplification. By employing an optimized first-order bi-directional Raman ampl ...