Access to long-chain polyketides by double-elongation reactions
Publications associées (59)
Graph Chatbot
Chattez avec Graph Search
Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.
AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.
Software synthesis is an attractive field of study that can promise a more safe and productive software development process. However, it is notoriously very difficult and few convincing applications have emerged so far. In this report, we present a series ...
This thesis is divided in four independent parts related to four different research projects. Each chapter describes one of the multiple aspects covered by organic chemistry, such as the generation of functional interfaces, understanding of biological proc ...
The HIV-1 Rev protein is responsible for shuttling partially spliced and unspliced viral mRNA out of the nucleus. This is a crucial step in the HIV-1 lifecycle, thus making Rev an attractive target for the design of anti-HIV drugs. Despite its importance, ...
A unique and practical synthetic sequence for rapid access to polyketides and to further the spiroacetals derived from them, which utilizes a bidirectional Hosomi-Sakurai allylation approach around key allylsilanes in the synthesis of the AB and CD ring sy ...
Polypropionates are common products of metabolism in bacteria, insects, fungi and marine organisms. They constitute an important class of products with a wide range of interesting biological activities. Our group has shown previously that 1-alkoxy-3-acylox ...
We have studied the distribution and community composition of denitrifying bacteria in the stratified water column and at the sediment-water interface in lakes Plusee and Schohsee, and a near-shore site in the Baltic Sea in Germany. Although environmental ...
Ligands based on bicyclic peptides can combine favourable properties of antibodies (good binding affinity and target specificity) and small molecule ligands (stability, access to chemical synthesis, diffusion properties) and might be suitable molecular str ...
A method has been developed to synthesise zinc oxide nanowire arrays that demonstrate superior device performance compared to conventional ZnO nanowires within dye sensitised solar cells (DSSCs). This simple yet effective methodology has produced nanowires ...
Combination of the surfactant-free nonaqueous sol-gel approach with the microwave technique makes it possible to synthesize Fe3O4, CoFe2O4, MnFe2O4, and NiFe 2O4 nanoparticles of about 5-6 nm and with high crystallinity and good morphological uniformity. T ...
Bicyclic peptides are small, constrained peptides that can bind with high affinity and selectivity to protein targets. Their small size provides a number of advantages over larger protein-based ligands, including access to chemical synthesis, better tissue ...