Cloning, localization and induction of mouse brain glycogen synthase
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BACKGROUND: Notch signaling regulates multiple differentiation processes and cell fate decisions during both invertebrate and vertebrate development. Numb encodes an intracellular protein that was shown in Drosophila to antagonize Notch signaling at binary ...
The olfactory system is a highly specialized chemodetector capable of discriminating between thousands of volatile chemical substances. This enormous capacity of chemical recognition is based on a large family of olfactory receptors (ORs). Despite the fact ...
The animal olfactory system represents the gold standard of olfactory biosensors with its capability to identify and discriminate thousands of odorant compounds. In order to mimic the performances of natural olfactory sensors it is necessary to develop met ...
Optical imaging techniques offer powerful solutions to capture brain networks processing in animals, especially when activity is distributed in functionally distinct spatial domains. Despite the progress in imaging techniques, the standard analysis procedu ...
BACKGROUND: Odorant receptors (ORs) are thought to act in a combinatorial fashion, in which odor identity is encoded by the activation of a subset of ORs and the olfactory sensory neurons (OSNs) that express them. The extent to which a single OR contribute ...
The content of vasoactive intestinal peptide (VIP) was determined by radioimmunoassay in different brain regions of three fish species, namely salmon, trout and carp. The VIP extracted from salmon brain was shown by reverse-phase high-performance liquid ch ...
Adenosine has been proposed as a key factor regulating the metabolic balance between energy supply and demand in the central nervous system. Because astrocytes represent an important cellular element in the control of brain energy metabolism, we investigat ...
The notion that long-term synaptic plasticity is generated by activity-induced molecular modifications is widely accepted. It is well established that neural cell adhesion molecule (NCAM) is one of the prominent modulators of synaptic plasticity. NCAM can ...
We have isolated nine putative odorant receptor genes from the chick, named COR1 to COR9, that belong to the large multigene family of olfactory G protein-coupled receptors found in the fish, rat, mouse, dog, and human. By combining genomic DNA blot analys ...
Much information is conveyed to animals by the diverse molecules propagated in their environment. This information is transmitted and treated within the olfactory system to be utilized by the rest of the brain. In this process, the sensory flow arriving fr ...
