Fast and accurate phylogenetic reconstruction from high-resolution whole-genome data and a novel robustness estimator
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Background: Leprosy has afflicted humankind throughout history leaving evidence in both early texts and the archaeological record. In Britain, leprosy was widespread throughout the Middle Ages until its gradual and unexplained decline between the 14th and ...
Background and aims - Recent methodological and theoretical advances in community ecology have allowed more robust exploration of complementary facets of biodiversity in plant communities. Focusing on semi-natural permanent grasslands of the French Jura Mo ...
National Botanic Garden of Belgium and Royal Botanical Society of Belgium2014
Background: In cell differentiation, a cell of a less specialized type becomes one of a more specialized type, even though all cells have the same genome. Transcription factors and epigenetic marks like histone modifications can play a significant role in ...
Background: Large-scale sequencing of genomes has enabled the inference of phylogenies based on the evolution of genomic architecture, under such events as rearrangements, duplications, and losses. Many evolutionary models and associated algorithms have be ...
As many whole genomes are sequenced, comparative genomics is moving from pairwise comparisons to multiway comparisons framed within a phylogenetic tree. A central problem in this process is the inference of data for internal nodes of the tree from data giv ...
Background and aims - Recent methodological and theoretical advances in community ecology have allowed more robust exploration of complementary facets of biodiversity in plant communities. Focusing on semi-natural permanent grasslands of the French Jura Mo ...
Epigenetic factors like histone modifications are known to play an important role in gene
regulation and cell differentiation. Recently, thanks to advances in technologies like ChIP-Seq
which is a high-throughput, high resolution, and low cost technology ...
The evolutionary relationships between organisms or phylogenies are fundamental to biology. They are invaluable as guiding tools to mine, organize and exploit the enormous amounts of biological data in the post-genomic era. The advent of high-throughput se ...
Background: Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential ro ...
The rapid accumulation of sequenced genomes offers the chance to resolve longstanding questions about the evolutionary histories, or phylogenies, of groups of organisms. The relatively rare occurrence of large-scale evolutionary events in a whole genome, e ...
