Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel
Graph Chatbot
Chattez avec Graph Search
Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.
AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.
We investigate the influence of curvature and topology on crystalline dimpled patterns on the surface of generic elastic bilayers. Our numerical analysis predicts that the total number of defects created by adiabatic compression exhibits universal quadrati ...
Receptors of the Cys-loop family are central to neurotransmission and primary therapeutic targets. In order to decipher their gating and modulation mechanisms, structural data is essential. However, structural studies require large amounts of pure, functio ...
Due to conservation of neuronal functioning across phyla, molecular targets of insecticides are similar in insects and vertebrates. Insecticides thus pose a risk to aquatic vertebrates,such as fish, and potentially cause neurotoxic effects. Although these ...
Studies have shown that both nicotine and sleep spindles are associated with enhanced memorisation. Further, a few recent studies have shown how cholinergic input through nicotinic and muscarinic receptors can trigger or modulate sleep processes in general ...
Human purinergic Gprotein-coupled receptor P2Y(1) (P2Y(1)R) is activated by adenosine 5'-diphosphate (ADP) to induce platelet activation and thereby serves as an important antithrombotic drug target. Crystal structures of P2Y(1)R revealed that one ligand ( ...
Bacteriophages of the myoviridae family, R-type pyocin, Photorhabus virulence cassette (PVC), Serratia antifeeding prophage (Afp) and type 6 secretion system (T6SS) form a class of contractile injection systems that share common structural and functional c ...
Visual backward masking (BM) deficits are often proposed to be trait markers for schizophrenia, revealing the genetic underpinnings of the disease. Here, we show that masking deficits in the shine-through effect are associated with polymorphisms in the nic ...
We present a combined analytical approach and numerical study on the stability of a ring bound to an annular elastic substrate, which contains a circular cavity. The system is loaded by depressurizing the inner cavity. The ring is modeled as an Euler-Berno ...
We investigate how the configurations obtained from the writhing of a heavy elastic rod are influenced by its intrinsic natural curvature. To this end, we perform a combination of numerics and precision model experiments on the compression or twisting of a ...
In this work, we consider the stability of a spherical shell under combined loading from a uniform external pressure and a homogenous natural curvature. Nonmechanical stimuli, such as one that tends to modify the rest curvature of an elastic body, are prev ...
