High-speed photography of the development of microdamage in trabecular bone during compression
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Motivated by applications in orthopaedic and maxillo-facial surgery, the mechanical behaviour of cortical bone in cyclic overloads at physiological strain rates is investigated. To this end, a new one-dimensional rate-independent constitutive model for com ...
Previous studies support resorbable biocomposites made of poly L-lactic acid (PLA) and β-tricalcium phosphate (TCP) produced by supercritical gas foaming as a suitable scaffold for tissue engineering. The present study was undertaken to demonstrate the bio ...
An obvious means to improve the fixation of a cancellous bone screw is to augment the surrounding bone with cement. Previous studies have shown that bone augmentation with Calcium Phosphate (CaP) cement significantly improves screw fixation. Nevertheless, ...
The aim of this paper is to show that damage mechanisms can account for the response of lamellar bone to nanoindentation tests, with particular regards to the decrease of indentation stiffness with increasing penetration depth and to the loss of contact st ...
Motivated by mechanical analysis of bones and bone-implant systems, a 3D constitutive law describing the macroscopic mechanical behaviour of both cortical and trabecular bone in cyclic (not fatigue) overloads is developed. The proposed model which mathemat ...
Deriaz O, Najafi B, Ballabeni P, Crettenand A, Gobelet C, Aminian K, Rizzoli R, Gremion G. Proximal tibia volumetric bone mineral density is correlated to the magnitude of local acceleration in male long-distance runners. J Appl Physiol 108: 852-857, 2010. ...
Tissue engineering scaffolds are porous structures that allow bone cells to reside and produce bone. This process involves migration and differentiation of mesenchymal stromal cells and production of cartilage and bone by chondrocytes and osteoblasts, whic ...
Bone is an amazing material evolved by nature to elegantly balance structural and metabolic needs in the body. Bone health is an integral part of overall health, but our lack of understanding of the ultrastructure of healthy bone precludes us from knowing ...
In clinical situations, bone defects are often located at load bearing sites. Tissue engineering scaffolds are future bone substitutes and hence they will be subjected to mechanical stimulation. The goal of this study was to test if cyclic loading can be u ...
Periostin (gene Postn) is a secreted extracellular matrix protein involved in cell recruitment and adhesion and plays an important role in odontogenesis. In bone, periostin is preferentially expressed in the periosteum, but its functional significance rema ...