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Life sciences have a constantly growing need for novel methodological approaches suitable to investigate the intracellular environment with increased temporal and spatial resolutions. Recently, optical near-field probes, such as laser-irradiated pointed me ...
Fluorescence microscopy techniques are well established research tools and have proven their use in a large variety of biomedical applications. Microscopic molecular contrast is achieved by imaging fluorescent dyes that bind specifically to a molecule of i ...
We report on the experimental and numerical demonstration of immersed submicron-size hollow focused spots, generated by structuring the polarization state of an incident light beam impinging on a micro-size solid immersion lens (μ-SIL) made of SiO2. Such s ...
Institute of Physics (IoP) and Deutsche Physikalische Gesellschaft2012
Magnetic resonance spectroscopic imaging (MRSI) is a powerful tool capable of providing spatially localized maps of metabolite concentrations. Its utility, however, is often depreciated by spectral leakage artifacts resulting from low spatial resolution me ...
Institute of Electrical and Electronics Engineers2013
Interest in high resolution imaging techniques has recently multiplied due to their importance in bio-medical research. Quantitative phase measurements by holographic microscopy is an extraordinary tool to gain new understanding of transparent biological s ...
We study the reflection of a tightly focused Gaussian beam off a near symmetric resonant tunneling structure comprising two identical coupled waveguides. The coupled waveguides are loaded on each side by a spacer layer and a high index prism. Reflection of ...
Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2012
We propose the combination of a planar optical resonator and a solid immersion lens for resonantly enhanced non-contact near-field lithography. Subwavelength small spots can be produced by exciting the Bessel modes of the resonator. (C) 2008 Optical Societ ...
Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2008
Transport of individual cells or chemical payloads on a subcellular scale is an enabling tool for the study of cellular com- munication, cell migration, and other localized phenomena. We present a magnetically actuated robotic system capable of fully autom ...
It is theoretically shown that by superimposing diffraction-free solutions of the Helmholtz equation, one can construct localized diffraction-free beams that pass through predetermined points on subwavelength distances. These beams are based on the phenome ...
We introduce an efficient, image formation model-based algorithm that extends super-resolution fluorescence localization to include orientation estimation, and report experimental accuracies of 5 nanometers for position estimation and 2 degrees for dipole ...