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The aim of this thesis is to optimise and gain fundamental information on two applications of photomedicine using fluorescence imaging and spectrofluorometry: (1) the detection of early bronchial cancer by autofluorescence imaging and (2) the endometrial a ...
A variety of homonuclear and heteronuclear transition metal carbonyl clusters have been analyzed by ultraviolet laser desorption/ionization time-of-flight mass spectrometry. The spectra were recorded in negative and positive ion modes, using both linear an ...
We report what is to our knowledge the first volume-holographic optical imaging instrument with the capability to return three-dimensional spatial as well as spectral information about semitranslucent microscopic objects in a single measurement. The four-d ...
We report on a distance control system for low-temperature scanning near-field optical microscopy, based on quartz tuning fork as shear force sensor. By means of a particular tuning fork optical fiber configuration, the sensor is electrically dithered by a ...
This paper presents a general method for obtaining the exact power spectra of generic time hopping modulated signals. Based on a point process approach, it provides simpler proofs for existing results and a powerful rigorous and at the same time systematic ...
We present a MEMS infrared spectrometer for selective and quantitative chemical gas analysis. infrared absorption spectroscopy can distinguish gases easily and also detect nonreactive molecules like CO2, in contrast to e.g. metal oxide gas sensors The foll ...
The environment is important for the exact course of a chemical reaction. As an example of the strong influence of the environment on the reaction, this work studies the isomerization reaction of the chromophore retinal in the binding pocket of the protein ...
We present the optical design and realization of a low-resolution liquid-crystal (LC) Fourier-transform spectrometer (FTS). This FTS is based on a polarization interferometer that has a Wollaston prism made of a LC material as a key component. It has a com ...
We report here a new method to obtain electronic spectra of biomolecular ions that are produced in the gas phase by electrospray and cooled to ~10K in a 22-pole ion trap, and we demonstrate this technique by applying it to protonated tryptophan and tyrosin ...
This paper describes a new monochromator design for a bending magnet beamline of the Swiss Light Source synchrotron facility. The beamline optics is based on a horizontally deflecting spherical grating monochromator (SGM) with two gratings at a constant de ...