Post-Surgical Interval And Lesion Location Within The Limbic Thalamus Determine Extent Of Retrosplenial Cortex Immediate-Early Gene Hypoactivity
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BACKGROUND: We have used a computational model of the thalamocortical system to investigate the effects of a GABAergic anesthetic (etomidate) on cerebral cortical and thalamic neuronal function. We examined the effects of phasic an tonic inhibition, as wel ...
Background: This study is based on the hypothesis that functional Magnetic Resonance Imaging (fMRI) indices in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia patients are spatially more heterogeneous than healthy controls for activation evoked ...
Cortical spreading depression (SD) has been suggested to underlie migraine aura. Despite a precise match in speed, the spatio-temporal patterns of SD observed in animal cortex and aura symptoms mapped to the cortical surface ordinarily differ in aspects of ...
The relationships between brain activity and accompanying hemodynamic and metabolic alterations, particularly between the cerebral metabolic rate of oxygen utilization (CMR(O2)) and cerebral blood flow (CBF), are not thoroughly established. CMR(O2) is clos ...
The distribution of vasoactive intestinal peptide (VIP) binding sites in the brain of several vertebrate species was examined by in vitro autoradiography on slide-mounted sections. This study included fish, frog, snake, pigeon, rat, mouse, guinea pig, cat ...
Huntington's disease (HD) pathology is well understood at a histological level but a comprehensive molecular analysis of the effect of the disease in the human brain has not previously been available. To elucidate the molecular phenotype of HD on a genome- ...
In order to characterize cortical responses to coherent motion we use magnetoencephalography (MEG) to measure human brain activity that is modulated by the degree of global coherence in a visual motion stimulus. Five subjects passively viewed two-phase mot ...
The complexity of processes occurring in the brain is an intriguing issue not just for scientists and medical doctors, but the humanity in general. The cortex ability to perceive and analyze an enormous amount of information in an instance of time, the par ...
Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways. Using diffusion spectrum imaging we noninvasively map these pathways within and across cort ...