Thioredoxin reductase, an emerging target for anticancer metallodrugs
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We report on a novel gas spectrometry technique using pyroelectric thin-him arrays. The 1 x 50 element arrays of PZT are integrated onto silicon using a membrane structure. The experimental characterization of the pyroelectric elements shows both high volt ...
Particle formation has been investigated experimentally from the initial molecular precursors up to the final micron-sized particles in a low pressure silane rf capacitive discharge. Neutrals and ions were studied by quadrupole mass spectrometry in power-m ...
The structural features of the active site of human monoamine oxidase B (MAO-B) were investigated by affinity labeling and site-directed mutagenesis. The pseudosubstrate inhibitor N-[2-aminoethyl]-5-chloro-2-pyridine carboxamide HCl (lazabemide) can be irr ...
The structure and absolute configuration of natural lentiginosine isolated from plant sources was determined to be (1S,2S,8aS)-1,2-dihydroxyindolizidine ((+)-4) on the basis of the synthesis of both enantiomers (+)-4 and (-)-4 and their inhibition of amylo ...
Methods and spectrometers for carrying out ion-cyclotron-resonance spectrometry are described in which a pulse sequence is employed which is described by P1-t1-P2-Tm-P3-t2, (P1, P2, and P3 are radio-frequency pulses, with P1 and P2 having the same frequenc ...
Electrolytic respirometry was used to determine the biodegradation kinetic parameters of five volatile aromatic organic compounds: benzene, 1,2‐dichlorobenzene, 1,3‐dichlorobenzene, 1,4‐dichlorobenzene, and 1,2,3‐trichlorobenzene. A protocol developed earl ...
The cluster beam technique offers promise of becoming a useful tool for chemists in their search for new compounds. Using this technique elemental vapors can be made to react under controlled conditions to form units of condensed matter (clusters) small en ...
Predissocn. spectra were detd. for SF6-Ar clusters in a mol. beam by monitoring the decrease in a specific mass spectrometer signals induced by a tunable continuous-wave CO2 laser. A red shift occurs downstream from the nozzle as the gas expands and the cl ...
The bacterial type VI secretion system (T6SS) is a macromolecular machine that injects effectors into prokaryotic and eukaryotic cells. The mode of action of the T6SS is similar to contractile phages: the contraction of a sheath structure pushes a tube top ...
