SurvJamda: an R package to predict patients' survival and risk assessment using joint analysis of microarray gene expression data
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Higher-order asymptotics provide accurate approximations for use in parametric statistical modelling. In this thesis, we investigate using higher-order approximations in two-specific settings, with a particular emphasis on the tangent exponential model. Th ...
The use of omics is gaining importance in the field of nanoecotoxicology; an increasing number of studies are aiming to investigate the effects and modes of action of engineered nanomaterials (ENMs) in this way. However, a systematic synthesis of the outco ...
Estimation of causal effects using machine learning methods has become an active research field in econometrics. In this paper, we study the finite sample performance of meta-learners for estimation of heterogeneous treatment effects under the usage of sam ...
There is a growing need for unbiased clustering algorithms, ideally automated to analyze complex data sets. Topological data analysis (TDA) has been used to approach this problem. This recent field of mathematics discerns characteristic features of a space ...
DNA methylation (DNAm) is one of the most frequently studied epigenetic mechanisms facilitating the interplay of genomic and environmental factors, which can contribute to externalizing behaviours and related psychiatric disorders. Previous epigenome-wide ...
We consider a setup in which confidential i.i.d. samples X1, . . . , Xn from an unknown finite-support distribution p are passed through n copies of a discrete privatization chan- nel (a.k.a. mechanism) producing outputs Y1, . . . , Yn. The channel law gua ...
Microarray gene expression data sets are jointly analyzed to increase statistical power. They could either be merged together or analyzed by meta-analysis. For a given ensemble of data sets, it cannot be foreseen which of these paradigms, merging or meta-a ...
In this work, we test the employment impact of distinct types of innovative investments using a representative sample of Spanish manufacturing firms over the period 2002-2013. Our GMM-SYS estimates generate various results, which are partially in contrast ...
Using an unbiased high-throughput microRNA (miRNA)-silencing screen combined with functional readouts for mitochondrial oxidative capacity in C2C12 myocytes, we previously identified 19 miRNAs as putative regulators of skeletal muscle mitochondrial metabol ...
We consider a setup in which confidential i.i.d. samples X1, ..., Xn from an unknown discrete distribution PX are passed through a discrete memoryless privatization channel (a.k.a. mechanism) which guarantees an epsilon-level of local differential privacy. ...