Publication
Single-Metabolite Bio-Nano-Sensors and System for Remote Monitoring in Animal Models
Giovanni De Micheli, Sandro Carrara, Eric Meurville, Cristina Boero, Andrea Cavallini, Léandre Bolomey
2011
Article de conférence
2011
Article de conférence
Résumé
A novel system for remote monitoring of metabolism in animal model is proposed in this paper. The system is obtained by integrating Bio-Nano-Sensors to detect single- metabolites, an electrochemical front-end made with off- the-shelf components, an RF communication sub-system, and an antenna of new design. The system has been calibrated and tested for continuous monitoring of four different metabolites: glucose, lactate, glutamate, and adenosine triphosphate (ATP). Tests with animal models (mice) have been conducted to investigate tissue inflammation induced by the implanted Bio-Nano- Sensors. The tests confirmed that our system is suitable and reliable for remote monitoring of single-metabolites in experiments with animal models.
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