Publication
Detection of an antioxidant profile in the human brain in vivo via double editing with MEGA-PRESS
Publications associées (32)
HaloTag-Based Tools for Live-Cell Imaging and Elucidation of Organellar Redox Biology
Redox homeostasis is a key factor in maintaining cellular function and health. The main determinant of the intracellular redox potential is ubiquitous glutathione (GSH) together with its oxidized dimer (GSSG). Importantly, both redox equilibrium and GSH ho ...
EPFL2024Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills
Friedhelm Christoph Hummel, Takuya Morishita, Pierre Theopistos Vassiliadis, Elena Beanato, Esra Neufeld, Fabienne Windel, Maximilian Jonas Wessel, Traian Popa, Julie Duqué
Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...
Nature Portfolio2024Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia
Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva
Background and hypothesis: Redox dysregulation has been proposed as a convergent point of childhood trauma and the emergence of psychiatric disorders, such as schizophrenia (SCZ). A critical region particularly vulnerable to environmental insults during ad ...
2024Integrated Wireless Power, Data Communication, and Thermal Sensing System for Autonomous Multisite Brain Implants
Implanted medical devices (IMDs) have been widely developed to support the monitoring and recording of biological data inside the body or brain. Wirelessly powered IMDs, a subset of implantable electronics, have been proposed to eliminate the limitations r ...
EPFL2024Magnetism of Single Surface Adsorbed Atoms Studied with Radio-Frequency STM
This thesis investigates the magnetic properties of single atoms and molecules adsorbed on thin magnesium oxide decoupling layers, grown on a silver single crystal. To address these systems experimentally, we use a low temperature scanning tunneling micros ...
EPFL2024Correlative light and volume electron microscopy to study brain development
Recent advances in volume electron microscopy (EM) have been driving our thorough understanding of the brain architecture. Volume EM becomes increasingly powerful when cells and their subcellular structures that are imaged in light microscopy are correlate ...
OXFORD UNIV PRESS2023Scattering from Time-Modulated Transmission-Line Loads: Theory and Experiments in Acoustics
Romain Christophe Rémy Fleury, Matthieu Francis Malléjac
Scattering wave systems that are periodically modulated in time offer many new degrees of freedom to control waves in both the spatial and frequency domains. Such systems, albeit linear, do not conserve frequency and require the adaptation of the usual the ...
2023Programmable Silicon Nitride Photonic Integrated Circuits
Tobias Kippenberg, Rui Ning Wang, Anat Siddharth, Viacheslav Snigirev, Andrea Bancora, Andrey Voloshin, Vladimir Shadymov
Silicon Nitride (Si3N4) photonic integrated circuits (PICs) have emerged as core technology in a variety of applications ranging from LIDAR to quantum control and computing. However, the need for high-speed, low-voltage tuning and modulation has been a lon ...
IEEE2023Early motor skill acquisition in healthy older adults: brain correlates of the learning process
Friedhelm Christoph Hummel, Takuya Morishita, Pablo Maceira Elvira, Manon Chloé Durand-Ruel, Chang-Hyun Park, Maeva Moyne
Motor skill learning is a crucial process at all ages. However, healthy aging is often accompanied by a reduction in motor learning capabilities. This study characterized the brain dynamics of healthy older adults during motor skill acquisition and identif ...
OXFORD UNIV PRESS INC2023Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice
The brain and behavior are under energetic constraints, limited by mitochondrial energy transformation capacity. However, the mitochondria-behavior relationship has not been systematically studied at a brain-wide scale. Here we examined the association bet ...
2023