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Formation of the Long Range Dpp Morphogen Gradient

Publications associées (36)

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Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia

Andrew Charles Oates

The human gene AGTRL1 is an angiotensin II receptor-like gene expressed in vasculature, which acts as the receptor for the small peptide APELIN, and a co-receptor for Human Immunodeficiency Virus. Mammalian AGTRL1 has been shown to modulate cardiac contrac ...

2007

Visualizing odorant receptor trafficking in living cells down to the single-molecule level

Horst Vogel, Horst Pick, Jean-Manuel Segura, Valérie Jacquier

Despite the importance of trafficking for regulating G protein-coupled receptor signaling, for many members of the seven transmembrane helix protein family, such as odorant receptors, little is known about this process in live cells. Here, the complete lif ...

2006

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Early stages of hot-electron thermalization in small gold nanoparticles wrapped in an adsorbates shell have been investigated by femtosecond transient absorption spectroscopy. Type-I hot electrons thermalize in 800 fs (to form type-II hot electron) either ...

Elsevier2006

Olfaction appears to be mediated by a large family of odorant receptors (ORs) that accounts for ~ 1% of the human genome [1–4]. The functional characterization of these receptors has so far been hindered by their poor functional expression in the plasma me ...

EPFL2005

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Sequential stages in the life cycle of the ionotropic 5-HT3 receptor (5-HT3R) were resolved temporally and spatially in live cells by multicolor fluorescence confocal microscopy. The insertion of the enhanced cyan fluorescent protein into the large intrace ...

2004

Monitoring expression and clustering of the ionotropic 5HT3 receptor in plasma membranes of live biological cells

Horst Vogel, Rudolf Hovius, Horst Pick, Michael Mayer

The ionotropic 5HT3 receptor was expressed in transiently transfected mammalian cells, yielding an unprecedented high concn. of up to 12 million receptors per cell. Receptor traffic in the plasma membrane of live cells was obsd. continuously over 24 h by f ...

2003

We provide the definition and a complete characterization of regular affine processes. This type of process unifies the concepts of continuousstate branching processes with immigration and Ornstein-Uhlenbeck type processes. We show, and provide foundations ...

2003

Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity

Johan Auwerx

Hypertriglyceridemia is a frequent complication accompanying the treatment of patients with either retinoids or rexinoids, [retinoid X receptor (RXR)-selective retinoids]. To investigate the cellular and molecular basis for this observation, we have studie ...

2001

Functional immobilisation of the nicotinic acetylcholine receptor in tethered lipid membranes

Horst Vogel, Rudolf Hovius, Per Rigler

The nicotinic acetylcholine receptor from Torpedo was immobilised in tethered membranes. Surface plasmon resonance was used to quantify the binding of ligands and antibodies to the receptor. The orientation and structural integrity of the surface-reconstit ...

Elsevier2000

Luminal heterodimeric amino acid transporter defective in cystinuria

Lukas Kühn

Mutations of the glycoprotein rBAT cause cystinuria type I, an autosomal recessive failure of dibasic amino acid transport (b(0,+) type) across luminal membranes of intestine and kidney cells. Here we identify the permease-like protein b(0,+)AT as the cata ...

1999