Differential signaling via the same axon of neocortical pyramidal neurons
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Computations in cortical circuits are mediated by synaptic interactions between excitatory and inhibitory neurons, and yet we know little about their activity in awake animals. Here, through single and dual whole-cell recordings combined with two-photon mi ...
The distribution of synaptic efficacies in neocortex has an approximately lognormal shape. Many weak synaptic connections coexist with few very strong connections such that only 20% of synapses contribute 50% of total synaptic strength. Furthermore, recent ...
The thick-tufted layer V pyramidal (TTL5) neuron is a key neuron providing output from the neocortex. Although it has been extensively studied, principles governing its dendritic and axonal arborization during development are still not fully quantified. Us ...
Spike Timing Dependent Plasticity (STDP) is a temporally asymmetric form of Hebbian learning induced by tight temporal correlations between the spikes of pre- and postsynaptic neurons. As with other forms of synaptic plasticity, it is widely believed that ...
