Redistribution of synaptic efficacy between neocortical pyramidal neurons
Publications associées (33)
Graph Chatbot
Chattez avec Graph Search
Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.
AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.
Our brain has the capacity to analyze a visual scene in a split second, to learn how to play an instrument, and to remember events, faces and concepts. Neurons underlie all of these diverse functions. Neurons, cells within the brain that generate and trans ...
The neocortex is the most distinctive feature of the mammalian brain and it is considered to be the substrate of high-order cognitive functions. The nature and the arrangement of the diverse neuronal elements constituting its multiple areas have received l ...
The cortex must maintain balanced levels of neural activity to correctly integrate inputs and to provide contextually meaningful outputs. Neuronal excitation is counterbalanced by various forms of inhibition such as spike frequency adaptation, short- and l ...
Spike Timing Dependent Plasticity (STDP) is a temporally asymmetric form of Hebbian learning induced by tight temporal correlations between the spikes of pre- and postsynaptic neurons. As with other forms of synaptic plasticity, it is widely believed that ...
Humans and animals learn by modifying the synaptic strength between neurons, a phenomenon known as synaptic plasticity. These changes can be induced by rather short stimuli (lasting, for instance, only a few seconds), yet, in order to be useful for long-te ...
Modifications of synaptic efficacies are considered essential for learning and memory. However, it is not known how the underlying functional components of synaptic transmission change over long time scales. To address this question, we studied cortical sy ...
Changes of synaptic connections between neurons are thought to be the physiological basis of learning. These changes can be gated by neuromodulators that encode the presence of reward. We study a family of reward-modulated synaptic learning rules for spiki ...
Avermann M, Tomm C, Mateo C, Gerstner W, Petersen CC. Microcircuits of excitatory and inhibitory neurons in layer 2/3 of mouse barrel cortex. J Neurophysiol 107: 3116-3134, 2012. First published March 7, 2012; doi:10.1152/jn.00917.2011.-Synaptic interactio ...
Changes in synaptic efficacies need to be long-lasting in order to serve as a substrate for memory. Experimentally, synaptic plasticity exhibits phases covering the induction of long-term potentiation and depression (LTP/LTD) during the early phase of syna ...
Neocortical layer 5 (L5) pyramidal cells have at least two spike initiation zones: Na(+) spikes are generated near the soma, and Ca(2+) spikes at the apical dendritic tuft. These spikes interact with each other and serve as signals for synaptic plasticity. ...