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The present PhD thesis deals with the high temperature polymerization of methyl methacrylate in a continuous pilot scale process. The major aim is to investigate the feasibility of a polymerization process for the production of PMMA molding compound at tem ...
Peptide-synthetic hybrid block copolymers are most easily prepared via ring-opening polymerization of ?-amino acid N-carboxyanhydrides using appropriately end-functionalized synthetic polymers as the macroinitiator. This class of peptide-synthetic hybrid b ...
Carrier-mediated drug delivery has emerged as a powerful methodology for the treatment of various pathologies. The therapeutic index of traditional and novel drugs is enhanced via the increase of specificity due to targeting of drugs to a particular tissue ...
The invention discloses a method for the manuf. of a peptidic folding precursor (switch-peptide) stable and sol. at physiol. conditions, derived from a peptide having a potential for self-assembling and fibrillogenesis. Another object of the invention is t ...
Biologically-inspired peptide sequences have been explored as auxiliaries to mediate self-assembly of synthetic macromolecules into hierarchically organized solution and solid state nanostructures. Peptide sequences inspired by the coiled coil motif and "s ...
Challenges in nanotechnology today involve controlling dimensions, inter-particle spacing, surface coverage and behavior/response of functional nanostructures. Creating or placing nanostructures on surfaces is important for applications like data storage, ...
A new class of water-soluble, amphiphilic star block copolymers with a large number of arms was prepared by sequential atom transfer radical polymerization (ATRP) of n-butyl methacrylate (BMA) and poly-(ethylene glycol) methyl ether methacrylate (PEGMA). A ...
The self-assembly in aqueous solution of hybrid block copolymers consisting of amphiphilic ?-strand peptide sequences flanked by one or two PEG chains was investigated by means of circular dichroism spectroscopy, small-angle X-ray scattering, and transmiss ...
Nanostructures are known to exhibit novel optical, electrical, and magnetic and many other interesting physical properties and a lot of research has been invested on the synthesis and study of such structures in the recent years. The massive drive towards ...
