Publication
Wall properties of the apolipoprotein E-deficient mouse aorta
Publications associées (32)
Biomechanical analysis of cerebral arteries
The intent of this thesis is to study the function of elastin in cerebral arteries, its contribution into the aging process and its implication into different cerebral diseases and in particular cerebral aneurysms. As of today, little is known on the genes ...
EPFL2008Effect of elastin degradation on carotid wall mechanics as assessed by a constituent-based biomechanical model
Nikolaos Stergiopoulos, Sylvain Roy, Luca Augsburger, Edouard Fonck, Gilles Prod'Hom
Arteries display a nonlinear anisotropic behavior dictated by the elastic properties and structural arrangement of its main constituents, elastin, collagen, and vascular smooth muscle. Elastin provides for structural integrity and for the compliance of the ...
2007A theoretical model of the cellular calcium dynamics and vasomotion in muscular arteries
Muscular arteries possess the ability to control actively their lumen by altering the tone of the smooth muscle cells of the arterial wall, a property which is vital for a large number of the hemodynamical functions of the body. Arterial contraction is due ...
EPFL2006Effect of intimal shear and cyclic strech on arterial segments perfused in vitro
Hemodynamics have crucial role in the control of vascular tone, in the regulation of arterial remodeling, and in the production of mediators that maintain arterial function. Changes in hemodynamics forces induce profound alterations in vascular cell metabo ...
EPFL2005Evidence for signaling via gap junctions from smooth muscle to endothelial cells in rat mesenteric arteries: possible implication of a second messenger
Jean-Jacques Meister, Roger Sauser, Jean-Louis Bény, Michèle Koenigsberger, Philippe Pittet, Mathieu Lamboley
We investigated heterocellular communication in rat mesenteric arterial strips at the cellular level using confocal microscopy. To visualize Ca(2+) changes in different cell populations, smooth muscle cells (SMCs) were loaded with Fluo-4 and endothelial ce ...
Elsevier2005A constitutive formulation of arterial mechanics including vascular smooth muscle tone
Nikolaos Stergiopoulos, Martin Zulliger, Alexander Rachev
A pseudo-strain energy function (pseudo-SEF) describing the biomechanical properties of large conduit arteries under the influence of vascular smooth muscle (VSM) tone is proposed. In contrast to previous models that include the effects of smooth muscle co ...
2004Short-Term biomechanical adaptation of the rat carotid to acute hypertension: contribution of smooth muscle
Nikolaos Stergiopoulos, Jean-Jacques Meister
The biomechanical adaptation of the arterial wall to hypertension has been studied extensively in recent years; however, the exact biomechanical contribution of vascular smooth muscle cells (VSMCs) during the adaptation process in conduit vessels is not kn ...
Springer Verlag2001