Publication
Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro
Publications associées (74)
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EPFL2024Optical manipulation of plasmonic nanoparticles: Applications in surface chemistry and nano-optics
Optical tweezers are devices that can manipulate nano- and microparticles using a laser. The principle of optical tweezers is to apply a force to an object using the momentum of light. This force is very small, but it is sufficient to move things in the mi ...
EPFL2023Stabilizing Polymer Coatings Alter the Protein Corona of DNA Origami and Can Be Engineered to Bias the Cellular Uptake
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With DNA-based nanomaterials being designed for applicationsincellular environments, the need arises to accurately understand theirsurface interactions toward biological targets. As for any materialexposed to protein-rich cell culture conditions, a protein ...
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The understanding and manipulation of nanoscale analytes is a central theme in nanotechnology and has been one of the main driving forces behind the development of this field as we know it today. Furthermore, such a technology has the potential to also rev ...
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Cells are attractive as carriers that can help to enhance control over the biodistribution of polymer nanomedicines. One strategy to use cells as carriers is based on the cell surface immobilization of the nanoparticle cargo. While a range of strategies ca ...
AMER CHEMICAL SOC2021Biotin-NeutrAvidin Mediated Immobilization of Polymer Micro- and Nanoparticles on T Lymphocytes
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Cells are powerful carriers that can help to improve the delivery of nanomedicines. One approach to use cells as carriers is to immobilize the nanoparticulate cargo on the cell surface. While a plethora of chemical conjugation strategies are available to b ...
2021Born to be different: the formation process of Cu nanoparticles tunes the size trend of the activity for CO2 to CH4 conversion
We investigate the impact of the formation process of Cu nanoparticles on the distribution of adsorption sites and hence on their activity. Using molecular dynamics, we model formation pathways characteristic of physical synthesis routes as the annealing o ...
ROYAL SOC CHEMISTRY2021Chemistry and Analysis of Nanoparticle-Modified Living Cells
Conventional therapeutics are often limited by their targeting ability, resulting in harmful and potential fatal side-effects for the patients. Recently, new strategies have been developed to improve target specificity of drugs in order to generate more ef ...
EPFL2020Surface engineering of T cells with polymer nanoparticles to enhance drug delivery to the brain
Firstly, this thesis presents the in vivo evaluation of a previously developed model system that utilizes CD4+ TE/M cells decorated with up to 100 polystyrene based nanoparticles per cell by maleimide thiol conjugation. These nanoparticle T-cell conjugates ...
EPFL2020New approach for time-resolved and dynamic investigations on nanoparticles agglomeration
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Nanoparticle (NP) colloidal stability plays a crucial role in biomedical application not only for human and environmental safety but also for NP efficiency and functionality. NP agglomeration is considered as a possible process in monodispersed NP colloida ...
TSINGHUA UNIV PRESS2020