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Cytochrome c peroxidase (I) from Saccharomyces cerevisiae was subjected to directed mol. evolution to generate mutants with increased activity against ABTS [2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)]. Using a combination of DNA shuffling and s ...
Cytochrome c peroxidase (CCP) from Saccharomyces cerevisiae was subjected to directed mol. evolution to generate mutants with increased activity against the classical peroxidase substrate, guaiacol, thus changing the substrate specificity of CCP from the p ...
A new multiplexing schedule is derived for multiplexing holograms in photorefractive polymers which do not exhibit mono-exponential recording behavior. An M-number (M/#) of 0.3 was measured experimentally by recording 20 holograms of roughly equal strength ...
Hydroxyl radicals dominate daytime tropospheric chem., responsible for reactive removal of most trace gases (e.g., volatile org. compds.[VOC]), and is an active participant in the NO and NO2 cycle. Pump-and-probe LIDAR was used to examine the OH- chem. in ...
In the last few years several researchers have resorted to artificial evolution (e.g. genetic algorithms) and learning techniques (e.g. neural networks) for studying the interaction between learning and evolution. These studies have been conducted for two ...
Co-evolution (i.e. the evolution of two or more competing populations with coupled fitness) has several features that may potentially enhance the power of adaptation of artificial evolution. In particular, as discussed by Dawkins and Krebs [3], competing p ...
Many parameters have a significant influence on c-commerce evolution. This complicates the assessment of the requirements for and the consequences of e-sales adoption. In order to support the decisions of companies thinking about a possible e-sales channel ...
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This paper describes a new kind of genetic representation called analog genetic encoding (AGE). The representation is aimed at the evolutionary synthesis and reverse engineering of circuits and networks such as analog electronic circuits, neural networks, ...
A review with 15 refs. Directed mol. evolution of enzymes and proteins has emerged as an extremely powerful method to create proteins with novel properties, both for practical applications as well as for mechanistic studies. To demonstrate the underlying p ...