A double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T
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It has been suggested already more than 60 years ago to use polarized nuclei in particle scattering experiments1, but only with the discovery of the solid effect dynamic nuclear polarization process2 the realisation of polarized solid targets became possib ...
Nuclear magnetic resonance (NMR) signals with short T1 and T2, such as the 13C signal of glycogen, are difficult to localize in three dimensions without major signal loss. A pulse sequence that accomplishes the spatial localization of 1H-decoupled 13C NMR ...
Objective To evaluate a transverse electromagnetic (TEM), a circularly polarized (CP) (birdcage), and a 12-channel phased array head coil at the clinical field strength of B (0) = 3T in terms of signal-to-noise ratio (SNR), signal homogeneity, and maps of ...
We developed a short-echo-time (TE) sequence for proton localized spectroscopy by combining a 1D add-subtract scheme with a doubly slice-selective spin-echo (SE) sequence. The sequence preserves the full magnetization available from the selected volume of ...
A new lower rim substituted calix[8]arene bearing eight phosphine oxide moieties has been synthesized. The structure of 5,11,17,23,29,35,41,47-octa(1,1,3,3-tetramethylbutyl)-49,50,51,52,53,54,55,56-octakis(dimethylphosphinoylmethyleneoxy)calix[8]arene (S) ...
Microfabricated small-volume NMR probes consisting of electroplated planar microcoils integrated on a glass substrate with etched microfluidic channels are fabricated and tested. 1H NMR spectra are acquired at 300MHz with three different probes having obse ...
The LCModel method was adapted to analyze localized in vivo (13)C NMR spectra obtained from the rat brain in vivo at 9.4 T. Prior knowledge of chemical-shifts, J-coupling constants and J-evolution was included in the analysis. Up to 50 different isotopomer ...
By analogy to heteronuclear systems, coherence can be transferred adiabatically in the rotating frame between two selected spins I and S belonging to a homonuclear network of scalar-coupled spins. In contrast to cross polarization with const. radiofrequenc ...
The implementation of a "fast, automatic shimming technique by mapping along projections" (FASTMAP) on a 2.1-Tesla whole-body system is described. The method provides a localized adjustment of all first- (X, Y, Z) and second-order (Z2, ZX, ZY, X2-Y2, 2XY) ...
Broadband proton decoupling of the entire 13C spectrum was possible within power absorption guidelines and resulted in the detection of narrow (as low as 2-3 Hz), natural abundance signals from metabolites such as myo- inositol, glutamate, N-acetyl-asparta ...