Publication
X-ray structure of the mouse serotonin 5-HT3 receptor
Publications associées (39)
Organ Neuroprosthetics: Connecting Transplanted and Artificial Organs with the Nervous System
Implantable neural interfaces with the central and peripheral nervous systems are currently used to restore sensory, motor, and cognitive functions in disabled people with very promising results. They have also been used to modulate autonomic activities to ...
Wiley2024Reconstruction of nerve functional topography using recruitment curves enables selective electrical stimulation
Silvestro Micera, Simone Romeni, Bianca Ziliotto
Multi-polar stimulation protocols have been used in the past to increase the selectivity of electrical stimulation of the nervous system. Nonetheless, the number of possible multipolar stimulation protocols is prohibitively large and cannot be explored dur ...
IEEE2023Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease
Hilal Lashuel, Florian Lang, Joan Romani Aumedes, Yogesh Singh
Background Braak's hypothesis states that sporadic Parkinson's disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulation of alpha-Synuclei ...
BMC2023A conditional glutamatergic synaptic vesicle marker for Drosophila
Evelyne Ruchti, Brian Donal McCabe
Glutamate is a principal neurotransmitter used extensively by the nervous systems of all vertebrate and invertebrate animals. It is primarily an excitatory neurotransmitter that has been implicated in nervous system development, as well as a myriad of brai ...
OXFORD UNIV PRESS INC2022A method to establish functional vagus nerve topography from electro-neurographic spontaneous activity
Silvestro Micera, Simone Romeni
Bioelectronic medicine is an emerging approach to treat many types of diseases via electrical stimulation of the autonomic nervous system (ANS). Because the vagus nerve (VN) is one of the most important nerves controlling several ANS functions, stimulation ...
2022The matricellular protein Drosophila Cellular Communication Network Factor is required for synaptic transmission and female fertility
Evelyne Ruchti, Brian Donal McCabe
Within the extracellular matrix, matricellular proteins are dynamically expressed nonstructural proteins that interact with cell surface receptors, growth factors, and proteases, as well as with structural matrix proteins. The cellular communication networ ...
Bethesda2022Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers
Pentameric ligand-gated ion channels (pLGICs) of the Cys-loop receptor family are key players in fast signal transduction throughout the nervous system. They have been shown to be modulated by the lipid environment, however the underlying mechanism is not ...
NATURE RESEARCH2021Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing
Carl Petersen, Sylvain Crochet, Célia Roxane Gasselin, Benoît Hohl
Fast synaptic transmission relies upon the activation of ionotropic receptors by neurotransmitter release to evoke postsynaptic potentials. Glutamate and GABA play dominant roles in driving highly dynamic activity in synaptically connected neuronal circuit ...
CELL PRESS2021Simultaneous decoding of cardiovascular and respiratory functional changes from pig intraneural vagus nerve signals
Silvestro Micera, Simone Romeni, Ivo Strauss
Objective. Bioelectronic medicine is opening new perspectives for the treatment of some major chronic diseases through the physical modulation of autonomic nervous system activity. Being the main peripheral route for electrical signals between central nerv ...
IOP PUBLISHING LTD2021Soft, Implantable Bioelectronic Interfaces for Translational Research
Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Sébastien Jiguet, Ivan Furfaro, Evgenia Vladimirova Roussinova, Marco Capogrosso, Nicolas Vachicouras, Giuseppe Schiavone, Florian Dylan Fallegger, Beatrice Barra, Xiaoyang Kang, Andreas Rowald, Simon Borgognon, Ismael Seanez Gonzalez
The convergence of materials science, electronics, and biology, namely bioelectronic interfaces, leads novel and precise communication with biological tissue, particularly with the nervous system. However, the translation of lab‐based innovation toward cli ...
2020