Publication
Reconciling Utility with Privacy in Genomics
Publications associées (35)
Protecting and Evaluating Genomic Privacy in Medical Tests and Personalized Medicine
Jean-Pierre Hubaux, Jacques Rougemont, Erman Ayday, Jean Louis Raisaro
In this paper, we propose privacy-enhancing technologies for medical tests and personalized medicine methods that use patients' genomic data. Focusing on genetic disease-susceptibility tests, we develop a new architecture (between the patient and the medic ...
2013Privacy-Preserving Computation of Disease Risk by Using Genomic, Clinical, and Environmental Data
Jean-Pierre Hubaux, Jacques Fellay, Erman Ayday, Jean Louis Raisaro
According to many scientists and clinicians, genomics is the "next big thing" in the field of medicine. On one hand, decreasing costs in genome sequencing has been paving the way to better preventive and personalized medicine. On the other hand, genomic da ...
2013The Chills and Thrills of Whole Genome Sequencing
Jean-Pierre Hubaux, Erman Ayday
In recent years, whole genome sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a wide range of revol ...
2013Personal Use of the Genomic Data: Privacy vs. Storage Cost
Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro
In this paper, we propose privacy-enhancing technologies for personal use of the genomic data and analyze the tradeoff between genomic privacy and storage cost of the genomes. First, we highlight the potential privacy threats on the genomic data. Then, foc ...
2013Addressing the Concerns of the Lacks Family: Quantification of Kin Genomic Privacy
Jean-Pierre Hubaux, Mathias Jacques Jean-Marc Humbert, Amalio Telenti, Erman Ayday
The rapid progress in human-genome sequencing is leading to a high availability of genomic data. This data is notoriously very sensitive and stable in time. It is also highly correlated among relatives. A growing number of genomes are becoming accessible o ...
2013Genome analysis of Desulfotomaculum kuznetsovii reveals a physiological similarity with Pelotomaculum thermopropionicum
Desulfotomaculum kuznetsovii is a moderately thermophilic member of the polyphyletic spore-forming genus Desulfotomaculum in the family Peptococcaceae. This species is of interest because it originates from deep subsurface thermal mineral water at a depth ...
Genomic Stand Consort2013Computational analysis of ultraconserved non-coding DNA elements in vertebrate genomes
Recent advancements in DNA sequencing technologies, accompanied by parallel development of sophisticated computational methods, offer an unprecedented opportunity to explore and study the genetic material of many organisms. However, despite the tremendous ...
EPFL2013Privacy-Enhancing Technologies for Medical Tests Using Genomic Data
Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro
We propose privacy-enhancing technologies for medical tests and personalized medicine methods, which utilize patients’ genomic data. Focusing specifically on a typical disease-susceptibility test, we develop a new architecture (between the patient and the ...
2013Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls
Jacques Fellay, Amalio Telenti
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure have b ...
Public Library Science2013Privacy-Enhancing Technologies for Medical Tests Using Genomic Data
Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro
In this paper, we propose privacy-enhancing technologies for medical tests and personalized medicine methods, which utilize patients' genomic data. First, we highlight the potential privacy threats on genomic data and the challenges of providing privacy-pr ...
2012