Cis-regulatory elementCis-regulatory elements (CREs) or Cis''-regulatory modules (CRMs) are regions of non-coding DNA which regulate the transcription of neighboring genes. CREs are vital components of genetic regulatory networks, which in turn control morphogenesis, the development of anatomy, and other aspects of embryonic development, studied in evolutionary developmental biology. CREs are found in the vicinity of the genes that they regulate. CREs typically regulate gene transcription by binding to transcription factors.
Generation II reactorA generation II reactor is a design classification for a nuclear reactor, and refers to the class of commercial reactors built until the end of the 1990s. Prototypical and older versions of PWR, CANDU, BWR, AGR, RBMK and VVER are among them. These are contrasted to reactors, which refer to the early prototype of power reactors, such as Shippingport, Magnox/UNGG, AMB, Fermi 1, and Dresden 1. The last commercial Gen I power reactor was located at the Wylfa Nuclear Power Station and ceased operation at the end of 2015.
Référencement localLe référencement local est une technique d'optimisation web qui est apparue vers la fin de 2006. Cette technique consiste à créer une fiche d'entreprise sur la section carte des moteurs de recherche et de profiter ainsi d'affichages optimisés dans les pages de résultats de recherche, mais aussi sur les cartes. Egalement, avec la multiplication des services et sites d'informations permettant d'obtenir de la visibilité localisée, le référencement local consiste aujourd'hui à développer en complément une présence générale au sein de tout lieu visité par d'éventuelles cibles.
Pharmaceutical formulationPharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form. Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patients. For orally administered drugs, this usually involves incorporating the drug into a tablet or a capsule.
Video search engineA video search engine is a web-based search engine which crawls the web for video content. Some video search engines parse externally hosted content while others allow content to be uploaded and hosted on their own servers. Some engines also allow users to search by video format type and by length of the clip. The video search results are usually accompanied by a thumbnail view of the video. Video search engines are computer programs designed to find videos stored on digital devices, either through Internet servers or in storage units from the same computer.
Generation III reactorGeneration III reactors, or Gen III reactors, are a class of nuclear reactors designed to succeed Generation II reactors, incorporating evolutionary improvements in design. These include improved fuel technology, higher thermal efficiency, significantly enhanced safety systems (including passive nuclear safety), and standardized designs intended to reduce maintenance and capital costs. They are promoted by the Generation IV International Forum (GIF).
ThromboseThrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting") is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss. Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus.
Regulator geneA regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences, which encode regulatory genes, are often at the five prime end (5') to the start site of transcription of the gene they regulate. In addition, these sequences can also be found at the three prime end (3') to the transcription start site. In both cases, whether the regulatory sequence occurs before (5') or after (3') the gene it regulates, the sequence is often many kilobases away from the transcription start site.
Human genetic variationHuman genetic variation is the genetic differences in and among populations. There may be multiple variants of any given gene in the human population (alleles), a situation called polymorphism. No two humans are genetically identical. Even monozygotic twins (who develop from one zygote) have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting.
RénineLa rénine (également appelée angiotensinogénase) est une enzyme protéolytique du système rénine-angiotensine-aldostérone. Elle a été découverte par Robert Tigerstedt en 1898. Chez l'Homme, elle est codée par le gène REN, situé sur le chromosome 1. redresse=2|vignette|Rénine : du gène à la protéine La synthèse de la rénine par les cellules de l'appareil juxta-glomérulaire rénal s'effectue en réponse à : une baisse de la volémie ; une baisse de la pression de perfusion sanguine ; à une hyperkaliémie ; à une hyponatrémie.
