Single-cell RT-PCR, a technique to decipher the electrical, anatomical, and genetic determinants of neuronal diversity
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Silicon biosensor microprobes for the in vivo detection of neurotransmitters are equipped with removable clips for an on-chip functionalisation technique that allows a simple and comfortable but very local and reproducible deposition of sensitive layers on ...
BACKGROUND: Brain-derived neurotrophic factor (BDNF) is believed to be an important regulator of striatal neuron survival, differentiation, and plasticity. Moreover, reduction of BDNF delivery to the striatum has been implicated in the pathophysiology of H ...
We previously established parthenogenetic mouse embryonic stem cells (ESCs) and this study was subsequently conducted for elucidating the influence of oocyte parthenogenesis on gene expression profile of ESCs. ...
Recent advances in biosensing technologies have led to applications of biosensor probe arrays for rapid identification of biological agents such as drugs, gene expressions, proteins, cholesterol and fats in an input sample. However, monitoring the simultan ...
Background: Gene expression analysis has emerged as a major biological research area, with real-time quantitative reverse transcription PCR (RT-QPCR) being one of the most accurate and widely used techniques for expression profiling of selected genes. In o ...
DNA microarrays are an important tool with a variety of applications in gene expression studies, genotyping, pharmacogenomics, pathogen classification, drug discovery, sequencing and molecular diagnostics. They are having a strong impact in medical diagnos ...
Silicon biosensor microprobes for the in vivo detection of neurotransmitters are equipped with removable clips for an on-chip functionalisation technique that allows a simple and comfortable but very local and reproducible deposition of sensitive layers on ...
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BACKGROUND: In the field of neuroscience microarray gene expression profiles on anatomically defined brain structures are being used increasingly to study both normal brain functions as well as pathological states. Fluorescent tracing techniques in brain t ...
The patch-clamp technique has allowed detailed studies on the electrical properties of neurons. Dye loading through patch pipettes has allowed characterizing the morphological properties of the neurons. In addition, the patch-clamp technique also allows ha ...
The unique properties of single-wall carbon nanotubes (SWNTs) and the application of nanotechnology to the nervous system may have a tremendous impact in the future developments of microsystems for neural prosthetics as well as immediate benefits for basic ...