Publication

Simultaneous Multi-Harmonic Imaging of Nanoparticles in Tissues for Increased Selectivity

Publications associées (32)

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Optical imaging probes have played a major role in detecting and monitoring a variety of diseases. In particular, nonlinear optical imaging probes, such as second harmonic generating (SHG) nanoprobes, hold great promise as clinical contrast agents, as they ...

AMER CHEMICAL SOC2021

Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression

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Pancreatic neuroendocrine tumors (PanNET) comprise two molecular subtypes, relatively benign islet tumors (IT) and invasive, metastasis-like primary (MLP) tumors. Until now, the origin of aggressive MLP tumors has been obscure. Herein, using multi-omics ap ...

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Doubly resonant second-harmonic generation of a vortex beam from a bound state in the continuum

Nicolas Grandjean, Romuald Houdré, Jean-François Carlin, Matteo Galli, Jun Wang, Marco Clementi, Momchil Minkov

Second-harmonic generation in nonlinear materials can be greatly enhanced by realizing doubly resonant cavities with high quality factors. However, fulfilling such doubly resonant condition in photonic crystal (PhC) slab cavities is a long-standing challen ...

2020

Eigenmode Analysis in Plasmonics: Application to Second Harmonic Generation and Electron Energy Loss Spectroscopy

Gabriel David Bernasconi

Eigenmodes are central to the study of resonant phenomena in all areas of physics. However, their use in nano-optics seems to have been hindered and delayed for various reasons. First, due to their small size, the response of nanostructures to a far-field ...

EPFL2019

Second Harmonic Generation Dynamics in Plasmonic Nanoparticles

Olivier Martin, Jérémy Butet, Gabriel David Bernasconi

Due to its symmetry properties, second-harmonic generation in plasmonic nanostructures enables the observation of even-parity modes that couple weakly to the far field. Consequentially, those modes radiate less and thus have a longer lifetime. Using a full ...

SPIE-INT SOC OPTICAL ENGINEERING2018

Characterization of a B16-F10 melanoma model locally implanted into the ear pinnae of C57BL/6 mice

Witold Waldemar Kilarski, Esra Güç

The common experimental use of B16-F10 melanoma cells focuses on exploring their metastatic potential following intravenous injection into mice. In this study, B16-F10 cells are used to develop a primary tumor model by implanting them directly into the ear ...

2018

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Glioblastoma are notorious for their highly invasive growth, diffusely infiltrating adjacent brain structures that precludes complete resection, and is a major obstacle for cure. To characterize this "invisible" tumor part, we designed a high resolution mu ...

2018

In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

Rolf Gruetter, Cristina Ramona Cudalbu, Bernard Lanz, Carole Poitry-Yamate, Marta Lai

2018

Excitation and time resolved spectroscopy of SAW harmonics up to GHz regime in photolithographed GaAs devices

Pasquale Scarlino, Marco Scigliuzzo

In this work, we demonstrate the excitation of surface acoustic waves (SAW) harmonics up to GHz regime in photolitographed devices fabricated on gallium arsenide (GaAs) by acting on the IDT metallization ratio among the finger width and pitch. Specifically ...

2017

Optical second harmonic generation from nanostructured graphene: a full wave approach

Olivier Martin, Jérémy Butet, Gabriel David Bernasconi, Raziman Thottungal Valapu, Bruno Majérus

Optical second harmonic generation (SHG) from nanostructured graphene has been studied in the framework of classical electromagnetism using a surface integral equation method. Single disks and dimers are considered, demonstrating that the nonlinear convers ...

2017

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