Publication
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. In a recent issue of Science, two studies, Bridgeman et al. (2015) and Gentili et al. (2015), report a novel mechanism for propagating an antiviral signal between cells, based on the transfer of the cGAS enzymatic product, cyclic GMP-AMP (cGAMP), in viral particles.
Francesco Stellacci, Paulo Henrique Jacob Silva, Quy Ong Khac, Xufeng Xu, Rémi Andréa La Polla, Heyun Wang