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Digital confocal microscopy through a multimode fiber

Publications associées (59)

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Integration of High-performance Optoelectronic Nanowire-based Devices at Optical Fiber Tips

Fabien Sorin, Wei Yan, Inès Richard

We establish a facile and robust approach to integrate high-performance monocrystalline semiconducting nanowire-based optoelectronic devices at optical fiber tips. The multi-functional fibers exhibit excellent optical and optoelectronic properties, leading ...

OSA Publishing2018

Multimode fiber optical imaging using wavefront control

Nicolino Stasio

Optical microscopy enables us to observe at high resolution and with a large field of view objects otherwise invisible for the naked eye. This is why it is becoming a fundamental tool in biology and in diagnostics, where observation at cellular level can t ...

EPFL2017

Microscopy and digital light shaping through optical fibers

Damien Claude-Marie Loterie

Microscopy is an essential tool in medicine and biomedical research. Traditional microscopes rely on bulky optics, complicating their usage when studying live animal tissues. In addition, light cannot penetrate very far in most biological tissues due to sc ...

EPFL2017

Nanoscopy in nonlinear scanning fluorescence imaging systems

Grégoire Pierre Jean Laporte

In the last 30 years, superresolution in optical microscopy has been a major field of research. During this time, different techniques have been created to break the diffraction limit in order to make observations at a nanometric scale. Given that optical ...

EPFL2016

Confocal microscopy via multimode fibers: fluorescence bandwidth

Demetri Psaltis, Christophe Moser, Damien Claude-Marie Loterie

We recently described a method for confocal reflection imaging through fibers, as a way to increase contrast when imaging unstained biological specimens. Using a transmission matrix, focused spots can be created at the distal end of a fiber. The backscatte ...

Spie-Int Soc Optical Engineering2016

A 2016 competition to find the optimum software for 3D single-molecule localization microscopy will help practitioners choose the best tool for the job and spur further developments in the field. ...

Macmillan2016

Spatially Variant PSF Modeling and Image Deblurring

Ferréol Arnaud Marie Soulez

Most current imaging instruments have a spatially variant point spread function (PSF). An optimal exploitation of these instruments requires to account for this non-stationarity. We review existing models of spatially variant PSF with an emphasis on those ...

SPIE2016

Confocal microscopy through a multimode fiber using optical correlation

Demetri Psaltis, Christophe Moser, Damien Claude-Marie Loterie

We report on a method to obtain confocal imaging through multimode fibers using optical correlation. First, we measure the fiber's transmission matrix in a calibration step. This allows us to create focused spots at one end of the fiber by shaping the wave ...

Optical Soc Amer2015

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We propose the use of a high-refractive index glass microsphere in combination with a conventional fluorescence microscope for imaging sub-cellular organelles and biomolecules. The microsphere is placed on a sample that is immersed in water, collects the n ...

Spie-Int Soc Optical Engineering2015

Methods and apparatus for imaging with multimode optical fibers

Demetri Psaltis, Christophe Moser, Ioannis Papadopoulos, Salma Farahi

A multimode waveguide illuminator and imager relies on a wave front shaping system that acts to compensate for modal scrambling and light dispersion by the multimode waveguide. A first step consists of calibrating the multimode waveguide and a second step ...

2015