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Neural probe combining microelectrodes and a droplet-based microdialysis collection system for high temporal resolution sampling

Publications associées (37)

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C. Elegans Immobilization Using Deformable Microfluidics For In Vivo Studies Of Early Embryogenesis And Intestinal Microbiota

Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Li Dong, Xiaopeng Huang, Jingwei Zhang

The genome of the nematode Caenorhabditis elegans shows far-reaching similarities to that of humans. C. elegans is therefore considered as a powerful model organism in biological research related to humans, for instance for the study of human diseases. Suc ...

Ieee2017

Microfluidic-integrated vertical electrodes employed in impedance-based cytometry

Enrica Rollo

During the last decades, the growing interest for single-cell analysis has led to the creation of a number of microfluidic and lab-on-a chip (LOC) platforms for characterizing cellular samples. In that context label-free based platforms are minimally invas ...

EPFL2016

Since the first compartmentalized neuronal culture described by Robert B. Campenot in 1977, compartmentalized microfluidic devices have been widely used to engineer the cellular environment for cell culture. In previous research by Dr. Anja Kunze, a microf ...

EPFL2016

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We recently developed a neural probe allowing to capture at high temporal resolution nano-volume droplets of interstitial fluid from the brain organized in a segmented flow. In order to enable the analysis of these small volume and low concentration drople ...

2016

A Simple and Reliable PDMS and SU-8 Irreversible Bonding Method and Its Application on a Microfluidic-MEA Device for Neuroscience Research

Philippe Renaud, Arnaud Bertsch, Marc Olivier Heuschkel, Patrick Fraering, Sébastien Mosser, Yufei Ren, Shun-Ho Huang, Jingjing Chen

Polydimethylsiloxane (PDMS) and SU-8 are currently two very commonly used polymeric materials in the microfluidics field for biological applications. However; there is a pressing need to find a simple, reliable, irreversible bonding method between these tw ...

MDPI2015

The present invention generally relates to microfluidics, and to spray drying and other drying techniques. By at least partially drying fluids within a microfluidic channel, instead of or in addition to conventional spray drying techniques, better control ...

2014

Planar electrodes are increasingly used in therapeutic neural stimulation techniques such as functional electrical stimulation, epidural spinal cord stimulation and cortical stimulation. Recently, optimized electrode geometries have been shown to increase ...

IEEE2013

The present invention generally relates to microfluidics, and to spray drying and other drying techniques. Various embodiments of the invention are generally directed to systems and methods for drying fluids contained within a channel such as a microfluidi ...

2013

Optofluidic differential spectroscopy for absorbance detection of sub-nanolitre liquid samples

Wuzhou Song, Jianhang Yang

We present a novel optofluidic differential method for carrying out absorbance spectroscopy of subnanolitre volumes of liquid samples on a microfluidic chip. Due to the reduction of liquid volume, the absorbance detection in microfluidics is often hindered ...

Royal Society of Chemistry2012

This dissertation proposes a computational framework targeted at improving the design of currently employed retinal prostheses. The framework was used for analysing factors impacting the performance of prostheses in terms of electrical stimulation for reti ...

EPFL2011