Host and pathogen genomics of severe pediatric infections
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Vaccination is one of the most effective ways to protect people from being infected by infectious disease. However, it is often impractical to vaccinate all people in a community due to various resource constraints. Therefore, targeted vaccination, which v ...
Relentless progress in our knowledge of the nature and functional consequences of human genetic variation allows for a better understanding of the protracted battle between pathogens and their human hosts. Multiple polymorphisms have been identified that i ...
Pseudomonas entomophila is unique among Pseudomonas species in being able to activate a systemic immune response in both Drosophila larvae and adults. It has been subsequently shown that oral infections with high doses of this bacterium are highly pathogen ...
Background: There is an ever-increasing volume of data on host genes that are modulated during HIV infection, influence disease susceptibility or carry genetic variants that impact HIV infection. We created GuavaH (Genomic Utility for Association and Viral ...
For more than a century, it has been recognized that our genetic inheritance and our environment interact to shape who we are and how we act (nature vs. nurture), and the study of genetics has allowed us to explain why traits can vary dramatically betwee ...
Les progrès actuels dans la connaissance des variations génétiques humaines et de leurs conséquences fonctionnelles permettent de mieux comprendre la bataille millénaire que se livrent l'homme et les microbes. De nombreux polymorphismes modulant notre répo ...
Contact surveys and diaries have conventionally been used to measure contact networks in different settings for elucidating infectious disease transmission dynamics of respiratory infections. More recently, technological advances have permitted the use of ...
Infectious diseases, both in their endemic and epidemic forms, have shaped the human genome. Ecology has also contributed to geographically constrained pressures on human populations. There are now multiple examples of population-specific genetic variants ...
Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence of human infections followed regional climatic trends with outbreaks occurring dur ...
