Detection of hypoglycemic events through wearable sensors
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Specialized glucosensing neurons are present in the hypothalamus, some of which neighbor the median eminence, where the blood–brain barrier has been reported leaky. A leaky blood–brain barrier implies high tissue glucose levels and obviates a role for endo ...
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The invention relates to a viscosimetric sensor for monitoring an analyte level in a patient or in body fluids ex vivo. In particular, the invention relates to a sensor for monitoring analytes, such as glucose levels in a patient. The sensor comprises at l ...
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The continuous delivery of glucose to the brain is critically important to the maintenance of normal metabolic function. However, elucidation of the hormonal regulation of in vivo cerebral glucose metabolism in humans has been limited by the lack of direct ...
The time between i.v. injection of a glucose bolus and the time the glucose concn. peaked in the s.c. tissue was measured in pentobarbital-anesthetized rats with implanted 290-mm-diam. amperometric sensors. Boluses of 100, 200, and 400 mg/kg body wt. were ...
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Enantiomeric oligoribonucleotides (ent-RNA) up to a sequence length of 35, consisting of the (L-configurated) nucleosides ent-adenosine, ent-guanosine, ent-cytidine, ent-uridine, and 1-(b-L-ribofuranosyl)thymine were prepd. by automated synthesis from appr ...
A copolymer containing 88% 2-hydroxyethyl methacrylate (HEMA), 9% poly(ethylene glycol) (MW 18.5 kDa) tetra-acrylate and 3% ethylene dimethacrylate was prepared and evaluated for use as a biocompatible interface between glucose biosensors and tissue in the ...