InteractoMIX: a suite of computational tools to exploit interactomes in biological and clinical research
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Potential functionals have been introduced recently as an important tool for the analysis of coupled scalar systems (e.g. density evolution equations). In this contribution we investigate interesting properties of this potential. Using the tool of displace ...
Dedicated multisensory mechanisms in the brain represent peripersonal space (PPS), a limited portion of space immediately surrounding the body. Previous studies have illustrated the malleability of PPS representation through hand-object interaction, showin ...
Turkish Discourse Bank (TDB) is a 400K subcorpus of METU Corpus (Say et al., 002) annotated for discourse relations (Zeyrek et al., 2008; Zeyrek et al., 2009; Zeyrek et al., 2010). TDB was annotated using DATT, an annotation tool created for the sole purpo ...
Epimerisation between ribofuranose and arabinofuranose sugars is crucial in several biosynthetic pathways, but is typically challenging to monitor. Here, we have screened for fluorescent boronic acids that can be used as molecular probes for the specific d ...
Designing putative metabolic pathways is of great interest in synthetic biology. Retrobiosynthesis is a discipline that involves the design, evaluation, and optimization of de novo biosynthetic pathways for the production of high-value compounds and drugs ...
We will demonstrate plasmonic and metamaterial based integrated nano-biosensors and ultrasensitive infrared absorption spectroscopy. These systems by enabling monitoring of molecular-protein interactions in real-time within aqueous solutions can be importa ...
Today's quantum chemistry methods are extremely powerful but rely upon complex quantities such as the massively multidimensional wave function or even the simpler electron density. Consequently, chemical insight and a chemist's intuition are often lost in ...
The application of macrocycles to previously undruggable targets has aroused a great deal of interest in this structural class. Recent studies advance our understanding of the way macrocycles bind protein targets and provide new strategies and tools to gen ...
The procedures commonly used to evaluate the performance of objective quality metrics rely on ground truth mean opinion scores and associated confidence intervals, which are usually obtained via direct scaling methods. However, indirect scaling methods, su ...
We study the spectrum of local operators living on a defect in a generic conformal field theory, and their coupling to the local bulk operators. We establish the existence of universal accumulation points in the spectrum at large s, s being the charge of t ...