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Structural to functional synaptic conversion

Publications associées (35)

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Principles of Network Plasticity in Neocortical Microcircuits

András Ecker

Synaptic plasticity underlies our ability to learn and adapt to the constantly changing environment. The phenomenon of synapses changing their efficacy in an activity-dependent manner is often studied in small groups of neurons in vitro or indirectly throu ...

EPFL2023

Creating Trust by Abolishing Hierarchies

Mathias Josef Payer, Edouard Bugnion, Evangelos Marios Kogias, Adrien Ghosn, Charly Nicolas Lucien Castes, Neelu Shivprakash Kalani, Yuchen Qian

Software is going through a trust crisis. Privileged code is no longer trusted and processes insufficiently protect user code from unverified libraries. While usually treated separately, confidential computing and program compartmentalization are both symp ...

Association for Computing Machinery2023

Differential Visual Proteomics: Enabling the Proteome-Wide Comparison of Protein Structures of Single-Cells

Henning Paul-Julius Stahlberg, Anastasia Syntychaki

Proteins are involved in all tasks of life, and their characterization is essential to understand the underlying mechanisms of biological processes. We present a method called "differential visual proteomics" geared to study proteome-wide structural change ...

American Chemical Society (ACS)2019

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The geometries of axons, dendrites and their synaptic connections provide important information about their functional properties. These can be collected directly from measurements made on serial electron microscopy images. However, manual and automated se ...

2018

Elastic Program Transformations

Jonas Benedict Wagner

Performance and reliability are important yet conflicting properties of systems software. Software today often crashes, has security vulnerabilities and data loss, while many techniques that could address such issues remain unused due to performance concer ...

EPFL2017

An Overview of a New Sensor Calibration Platform

Jan Skaloud, Stéphane Guerrier, Philipp Clausen

Inertial sensors have been employed in different types of applications in miniature embedded devices such as phones, watches, and small unmanned aerial vehicles. The stochastic structure of the error signal coming from these sensors is complex and needs to ...

2017

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In the neocortex, inhibitory interneurons of the same subtype are electrically coupled with each other via dendritic gap junctions (GJs). The impact of multiple GJs on the biophysical properties of interneurons and thus on their input processing is unclear ...

Oxford University Press (OUP)2016

Genetic dissection of the role of BMP signaling for the development of the auditory brainstem nuclei and the large calyx of Held synapse

Elin Kristina Kronander

Synapses are key elements for communication within the complex network of neurons that make up our brain. Interestingly, synaptic connections can differ greatly in form and function, depending on the specific circuit into which they are embedded. In this P ...

EPFL2016

An algorithm to predict the connectome of neural microcircuits

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, James Gonzalo King

Experimentally mapping synaptic connections, in terms of the numbers and locations of their synapses and estimating connection probabilities, is still not a tractable task, even for small volumes of tissue. In fact, the six layers of the neocortex contain ...

Frontiers Research Foundation2015

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Computer-implemented methods, software, and systems for determining a distribution of neuronal cells across a portion of a brain are described. One computer-implemented method for determining a target distribution of one or more neuronal cells across a por ...

2014