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Feeding the human brain model

Publications associées (44)

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

EPFL2023

Noninvasive deep brain stimulation to modulate human behavior by means of transcranial temporal interference electrical stimulation

Elena Beanato

All functions we use in our everyday life depend on a complex interplay between both cortical and subcortical brain areas, communicating in between each others. When a region is affected by either an accident, aging or neurodegenerative diseases, the whole ...

EPFL2023

Investigating cognitive ability using action-based models of structural brain networks

Enrico Amico

Recent developments in network neuroscience have highlighted the importance of developing techniques for analysing and modelling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative models that use ...

OXFORD UNIV PRESS2022

Computational Concepts for Reconstructing and Simulating Brain Tissue

Felix Schürmann, Srikanth Ramaswamy, Jean-Denis Georges Emile Courcol

It has previously been shown that it is possible to derive a new class of biophysically detailed brain tissue models when one computationally analyzes and exploits the interdependencies or the multi-modal and multi-scale organization of the brain. These re ...

Springer2022

BLOOM: Bimodal Lattice One-out-of-Many Proofs and Applications

Ngoc Khanh Karol Nguyen

We give a construction of an efficient one-out-of-many proof system, in which a prover shows that he knows the pre-image for one element in a set, based on the hardness of lattice problems. The construction employs the recent zero-knowledge framework of Ly ...

SPRINGER INTERNATIONAL PUBLISHING AG2022

A Unified Framework for Neuroscience Morphological Data Visualization

Juan José García Cantero

The complexity of the human brain makes its understanding one of the biggest challenges that science is currently confronting. Due to its complexity, the brain has been studied at many different levels and from many disciplines and points of view, using a ...

2021

Molecular architecture of the developing mouse brain

Gioele La Manno, Alex Russell Lederer, Irina Khven

The mammalian brain develops through a complex interplay of spatial cues generated by diffusible morphogens, cell-cell interactions and intrinsic genetic programs that result in probably more than a thousand distinct cell types. A complete understanding of ...

NATURE PORTFOLIO2021

Hypoxia Conditioning as a Promising Therapeutic Target in Parkinson's Disease?

Hilal Lashuel, Grégoire Millet, Johannes Burtscher, Muhammed Muazzam Kamil Syed

Several lines of research point to a key role of low oxygen supply (hypoxia) in Parkinson's disease pathogenesis. Although severe hypoxia is detrimental for the brain, physiological adaptations to mild hypoxia are neuroprotective. Herein we discuss, how ne ...

WILEY2021

Exploring dynamic functional connectivity by incorporating prior knowledge of brain structure

Anjali Bagunu Tarun

The synchronized firing of distant neuronal populations gives rise to a wide array of functional brain networks that underlie human brain function. Given the enormous perception, learning, and cognition potential of the human brain, it is not surprising th ...

EPFL2020

The Scientific Case for Brain Simulations

Felix Schürmann, Michele Migliore, Alain Destexhe

A key element of the European Union's Human Brain Project (HBP) and other large-scale brain research projects is the simulation of large-scale model networks of neurons. Here, we argue why such simulations will likely be indispensable for bridging the scal ...

CELL PRESS2019

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