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Acetylated tubulin is essential for touch sensation in mice

Publications associées (34)

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Congruency effects can compensate for deficits of healthy older adults in crossmodal integration

Friedhelm Christoph Hummel

One of the pivotal challenges of aging is to maintain independence in the activities of daily life. In order to adapt to changes in the environment, it is crucial to continuously process and accurately combine simultaneous input from different sensory syst ...

2019

Spinal cord injury (SCI) leads to permanent deficits in sensory and motor function due to the physical disruption of descending and ascending pathways. As a consequence, spinal circuits below the level of lesion remain in an intact, but inactive state. A n ...

EPFL2019

In the mouse whisker system, sensory information is relayed to the whisker somatosensory cortex by two major thalamic nuclei, the ventral posterior medial nucleus (VPM) and the posterior medial nucleus (POM). While the cortical axonal innervation pattern o ...

EPFL2018

Upper limb amputation disrupts most daily activities and reduces the quality of life of affected individuals. Building a suitable prosthetic limb, which can restore at least some of the lost capabilities, is a goal which has been pursued for centuries. In ...

EPFL2018

Indoor environment as a multi-sensory experience: visual and thermal factor interactions

Marilyne Andersen, Jan Wienold, Giorgia Chinazzo

In our daily lives we are exposed simultaneously to multiple sensory stimuli, such as visual, thermal, acoustic and olfactory. Experienced together, they shape our perception of the environment and determine our comfort. In indoor environments, stimuli are ...

2018

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Interoceptive signals, such as the heartbeat, are processed in a network of brain regions including the insular cortex. Recent studies have shown that such signals modulate perceptual and cognitive processing, and that they impact visual awareness. For exa ...

2018

Two-photon calcium imaging of neocortical projection neurons in whisker somatosensory cortex during goal-directed sensorimotor learning

Dimitra Angeliki Vavladeli

Abstract Excitatory projection neurons of the neocortex are thought to play important roles in per-ceptual and cognitive functions of the brain by directly connecting diverse cortical and subcortical areas. However, many aspects of the anatomical and func ...

EPFL2018

Evolution of Acid-Sensing Olfactory Circuits in Drosophilids

Matteo Dal Peraro, Benoîte Bargeton

Animals adapt their behaviors to specific ecological niches, but the genetic and cellular basis of nervous system evolution is poorly understood. We have compared the olfactory circuits of the specialist Drosophila sechellia-which feeds exclusively on Mori ...

Elsevier2017

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Recent studies have highlighted the role of multisensory integration as a key mechanism of self-consciousness. In particular, integration of bodily signals within the peripersonal space (PPS) underlies the experience of the self in a body we own (self-iden ...

Elsevier2017

Parallel pathways from whisker and visual sensory cortices to distinct frontal regions of mouse neocortex

Carl Petersen, Varun Sreenivasan, Céline Matéo, Alexandros Kyriakatos

The spatial organization of mouse frontal cortex is poorly understood. Here, we used voltage-sensitive dye to image electrical activity in the dorsal cortex of awake head-restrained mice. Whisker-deflection evoked the earliest sensory response in a localiz ...

SPIE-Intl Soc Optical Eng2017