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Microfluidic device and method for isolation of nucleic acids

Publications associées (98)

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Three-dimensional electrodes for dielectrophoretic applications

Kevin Keim

This thesis reports the use of metal-coated three-dimensional SU-8 electrodes for dielectrophoretic bio sensing and particle manipulation applications. Placing free standing three-dimensional electrodes in microfluidic channels, electric fields can be appl ...

EPFL2020

Microscopic Detection Analysis of Single Molecules in MoS2 Membrane Nanopores

Aleksandra Radenovic, Michael Graf

A systematic microscopic analysis of the various resistive effects involved in the electronic detection of single biomolecules in a nanopore of a MoS2 nanoribbon is presented. The variations of the transverse electronic current along the two-dimensional (2 ...

2020

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Mitochondrial respiration is a key signature for the assessment of mitochondrial functioning and mitochondrial dysfunction is related to many diseases including metabolic syndrome and aging-associated conditions. Here, we present a microfluidic Caenorhabdi ...

ROYAL SOC CHEMISTRY2020

Characterization of Coenzyme Q Biosynthesis Proteins through Integrative Modeling at the Protein-Membrane Interface

Deniz Aydin

Integral and peripheral membrane proteins account for one-third of the human proteome, and they are estimated to represent the target for over 50% of modern medicinal drugs. Despite their central role in medicine, the complex, heterogeneous and dynamic nat ...

EPFL2019

Programmable Aerodynamic Drag on Active Dimpled Cylinders

Pedro Miguel Nunes Pereira de Almeida Reis, Dong Yan, Mark Andrew Guttag

This study demonstrates that the aerodynamic drag profile of a patterned deformable cylinder at high Reynolds numbers can be programmed, on demand, by modifying its topography through pneumatic actuation. The samples used in the experiments comprise a rigi ...

WILEY-V C H VERLAG GMBH2019

Mechanics of a pressure-controlled adhesive membrane for soft robotic gripping on curved surfaces

Jamie Paik, Metin Sitti, Sukho Song

This paper aims at understanding the adhesion mechanics of a pressure-controlled adhesive thin elastomeric membrane for soft robotic gripping on non-planar, curved surfaces. The adhesive elastic membrane is lined with gecko-inspired microfiber arrays and c ...

2019

Capsules with thin shells have a high‐loading capacity and are thus well‐suited containers for reagents that must be stored in confined volumes. Capsules contained in larger capsules, so‐called double capsules, allow the encapsulation of distinct reagents ...

2018

Label-free and charge-sensitive dynamic imaging of lipid membrane hydration on millisecond time scales

Sylvie Roke, Orly Bagunu Tarun

Biological membranes are highly dynamic and complex lipid bilayers, responsible for the fate of living cells. To achieve this function, the hydrating environment is crucial. However, membrane imaging typically neglects water, focusing on the insertion of p ...

2018

Large Array of Shape Memory Polymer Actuators for Haptics and Microfluidics

Nadine Besse

My thesis advances the field of shape memory polymer (SMP) actuators by providing a versatile strategy to arbitrarily reconfigure large arrays of densely packed latching soft actuators. It exploits two key intrinsic characteristics of SMPs, which are their ...

EPFL2018

We have used fluorescence nanoscopy for direct imaging of adsorption of individual colloidal quantum dots of diameter similar to 10 nm (spherical core/shell CdSeS/ZnS semiconductor nanocrystals, functionalized by organic oleic acid ligands) in nanopores of ...

2018