Publication
Diazepam actions in the VTA enhance social dominance and mitochondrial function in the nucleus accumbens by activation of accumbal dopamine D1 receptors
Publications associées (45)
Medial Forebrain Bundle Deep Brain Stimulation has Symptom-specific Anti-depressant Effects in Rats and as Opposed to Ventromedial Prefrontal Cortex Stimulation Interacts With the Reward System
Background: In recent years, deep brain stimulation (DBS) has emerged as a promising treatment option for patients suffering from treatment-resistant depression (TRD). Several stimulation targets have successfully been tested in clinical settings, includin ...
Elsevier Science Inc2015Automatic target validation based on neuroscientific literature mining for tractography
Jean-Cédric Chappelier, Sean Lewis Hill, Jocelyne Bloch, Bogdan Draganski, Renaud Luc Richardet, Xavier Vasques, David Slater
Target identification for tractography studies requires solid anatomical knowledge validated by an extensive literature review across species for each seed structure to be studied. Manual literature review to identify targets for a given seed region is ted ...
Frontiers Research Foundation2015Long-term behavioral programming induced by peripuberty stress in rats is accompanied by GABAergic-related alterations in the amygdala
Maria del Carmen Sandi Perez, Stamatina Tzanoulinou, Vandana Veenit
Stress during childhood and adolescence is a risk factor for psychopathology. Alterations in γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain, have been found following stress exposure and fear experiences and are often implica ...
Public Library of Science2014Social deficits induced by peripubertal stress in rats are reversed by resveratrol
Maria del Carmen Sandi Perez, Olivia Zanoletti, Guillaume Poirier
Adolescence is increasingly recognized as a critical period for the development of the social system, through the maturation of social competences and of their underlying neural circuitries. The present study sought to test the utility of resveratrol, a di ...
2014Neurofeedback-mediated self-regulation of the dopaminergic midbrain
Roger Gassert, Maria Laura Blefari
The dopaminergic system is involved in reward encoding and reinforcement learning. Dopaminergic neurons from this system in the substantia nigra/ventral tegmental area complex (SN/VTA) fire in response to unexpected reinforcing cues. The goal of this study ...
Elsevier2013Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function
Patrick Aebischer, Bernard Schneider, Sylvain Eric Lengacher, Julien Dusonchet
Mitochondrial dysfunction and oxidative stress have been implicated in the etiology of Parkinsons disease. Therefore, pathways controlling mitochondrial activity rapidly emerge as potential therapeutic targets. Here, we explore the neuronal response to pro ...
Oxford University Press2012Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease
Elpida Tsika, Darren Moore, Alzbeta Trancikova
Mitochondria are highly dynamic, multifunctional organelles. Aside from their major role in energy metabolism, they are also crucial for many cellular processes including neurotransmission, synaptic maintenance, calcium homeostasis, cell death, and neurona ...
2012Encoding of Marginal Utility across Time in the Human Brain
Marginal utility theory prescribes the relationship between the objective property of the magnitude of rewards and their subjective value. Despite its pervasive influence, however, there is remarkably little direct empirical evidence for such a theory of v ...
2009Risk and Reward Perception in the Human Brain
Anjali Devi Vanapilli Nursimulu
The recent spate of neuroimaging studies on decision-making under uncertainty has provided converging evidence of a spatio-temporal dissociation of risk and expected reward encoding in the human brain. While this research has demonstrated widespread hemody ...
University of Zurich2007Neural antecedents of financial decisions
To explain investing decisions, financial theorists invoke two opposing metrics: expected reward and risk. Recent advances in the spatial and temporal resolution of brain imaging techniques enable investigators to visualize changes in neural activation bef ...
2007