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Tyrosinase is a type I membrane protein found in melanosomes, which are lysosomal-like organelles and specific for pigment cells. A mutation of mouse tyrosinase, platinum (cp), leads to truncation of tyrosinase's cytosolic tail, and results in misrouting t ...
We use cryo-electron microscopy to compare 3D shapes of 158 bp long DNA minicircles that differ only in the sequence within an 18 bp block containing either a TATA box or a catabolite activator protein binding site. We present a sorting algorithm that corr ...
An ever more complete picture of the organization and function of the endocytic pathway is emerging. New mechanisms, and in particular lipid- based mechanisms that couple membrane dynamics and sorting, are being unraveled. But the final picture is still co ...
DNA is a long polymer with the form of a double helix of about two nanometers diameter (2.10-9 meters). It is composed of nucleotides whose sequence carries the information of heredity. The four possible nucleotides have slightly different geometries, and ...
Continuous queries over data streams typically produce large volumes of result streams. To scale up the system, one should carefully study the problem of delivering the result streams to the end users, which, unfortunately, is often over-looked in existing ...
We propose a new exact Euclidean distance transformation (DT) by propagation, using bucket sorting. A fast but approximate DT is first computed using a coarse neighborhood. A sequence of larger neighborhoods is then used to gradually improve this approxima ...
The study of genomic inversions (or reversals) has been a mainstay of computational genomics for nearly 20 years. After the initial breakthrough of Hannenhalli and Pevzner, who gave the first polynomial-time algorithm for sorting signed permutations by inv ...
In order to cope with sustainable development policy, buildings should be at least healthy, comfortable and energy efficient. Criteria for assessing individually the occupant's perceived health, the provided thermal, visual, acoustical comfort, the indoor ...
Inspired by the combinatorial denoising method {\tt DUDE} \cite{WOSVW04}, we present efficient algorithms for implementing this idea for arbitrary contexts or for using it within subsequences. We also propose effective, efficient denoising error estimators ...
