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Exploring the inhibition mechanism of adenylyl cyclase type 5 by n-terminal myristoylated Gαi1

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Exploring the inhibition mechanism of adenylyl cyclase type 5 by n-terminal myristoylated Gαi1

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From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

Computationally designed GPCR quaternary structures bias signaling pathway activation

Computational rewiring of allosteric pathways reprograms GPCR selective responses to ligands

Hitting the Bullseye: Endogenous Electrophiles Show Remarkable Nuance in Signaling Regulation

Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design

Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5

Computationally designed GPCR quaternary structures bias signaling pathway activation

The role of metal ions in G protein-coupled receptor signalling and drug discovery

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

The role of metal ions in G protein-coupled receptor signalling and drug discovery

Computationally designed GPCR quaternary structures bias signaling pathway activation

Computationally designed GPCR quaternary structures bias signaling pathway activation

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Computational rewiring of allosteric pathways reprograms GPCR selective responses to ligands

From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5

Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design

Hitting the Bullseye: Endogenous Electrophiles Show Remarkable Nuance in Signaling Regulation

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities