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Exploring the inhibition mechanism of adenylyl cyclase type 5 by n-terminal myristoylated Gαi1

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Exploring the inhibition mechanism of adenylyl cyclase type 5 by n-terminal myristoylated Gαi1

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From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

Computationally designed GPCR quaternary structures bias signaling pathway activation

Computational rewiring of allosteric pathways reprograms GPCR selective responses to ligands

Hitting the Bullseye: Endogenous Electrophiles Show Remarkable Nuance in Signaling Regulation

Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design

Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5

Computationally designed GPCR quaternary structures bias signaling pathway activation

The role of metal ions in G protein-coupled receptor signalling and drug discovery

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

From Sequence to Dynamics to Function: Computational Design of Allostery and Ligand Selectivity in G-Protein Coupled Receptors

Computationally designed GPCR quaternary structures bias signaling pathway activation

Computationally designed GPCR quaternary structures bias signaling pathway activation

Computational rewiring of allosteric pathways reprograms GPCR selective responses to ligands

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design

Hitting the Bullseye: Endogenous Electrophiles Show Remarkable Nuance in Signaling Regulation

Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities

The role of metal ions in G protein-coupled receptor signalling and drug discovery