Publication
Organs-on-chip monitoring: sensors and other strategies
Publications associées (34)
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We present a new cell culture technology for large-scale mechanobiology studies capable of generating and applying optically controlled uniform compression on single cells in 3D. Mesenchymal stem cells (MSCs) are individually encapsulated inside an optical ...
ROYAL SOC CHEMISTRY2022Device and process for tissue-engineering and regenerative medicine
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A process and device for direct in-vitro to in-vivo transfer of a living microcarrier culture by controlled dehydration into a viscoelastic material capable of cell-protection during delivery. One particular purpose of the present invention is that of prov ...
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Carlotta Guiducci, Samuel Kilchenmann, Kevin Keim, Paul Karoly Otto Ery, Mohamed Zakarya Alsaid Ali Rashed
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2019Engineered peptide macrocycles can inhibit matrix metalloproteinases with high selectivity
Christian Heinis, Xudong Kong, Jonas Alfred Karl Wilbs, Jeremy Touati, Michal Sabisz, Alice Baumann
Matrix metalloproteinases (MMPs) are zinc‐dependent endopeptidases at the intersection of health and disease due to their involvement in processes such as tissue repair and immunity as well as cancer and inflammation. Because of the high structural conserv ...
2019Pore Size Manipulation in 3D Printed Cryogels Enables Selective Cell Seeding
Philippe Renaud, Arnaud Bertsch, Thomas Michael Braschler, Ariane Rochat, Amélie Barbara Hildegarde Béduer, Ludovic Serex, Aleksandra Filippova
Cryogels are macroporous materials that display remarkable properties, such as high pore interconnection, large surface to volume ratio, and high mechanical stability, making them good candidates for 3D cell culture. However, shaping cryogels remains chall ...
2018Subsurface ablation of tissue by ultrafast laser
Thomas Jean Victor Marie Lanvin
Laser-induced optical breakdown (LIOB) is a multiphoton process which can be used for selective removal of material. It revolves around the creation of a plasma in the focal volume of a beam, and requires very high peak intensities in the order of the GW.c ...
EPFL2017Dielectric Elastomer Actuator for Mechanical Loading of 2D Cell Cultures
Herbert Shea, Samuel Rosset, Alexandre Poulin
We demonstrate the use of dielectric elastomer actuators (DEAs) for mechanical stimulation of cells in vitro. The development of living tissues is regulated by their mechanical environment through the modification of fundamental cellular functions such as ...
Royal Society of Chemistry2016Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System
Peter Frey, Jeffrey Alan Hubbell, Hans Mattias Larsson, Elif Vardar, Kalitha Pinnagoda, Mouti Elodie Mouloungui
Ureteral replacement by tissue engineering might become necessary following tissue loss after excessive ureteral trauma, after retroperitoneal cancer, or even after failed reconstructive surgery. This need has driven innovation in the design of novel scaff ...
Mary Ann Liebert, Inc2015Enzyme SU-8 microreactors: simple tools for cell-culture monitoring
Nico de Rooij, Peter Van der Wal, Sara Talaei, Martha Liley
Monitoring metabolism fluctuations inside a cell culture is a valuable method for assessment of the cells vitality. Enzyme-based biosensors can provide selective measurement of metabolites such as glucose, lactate, glutamate and choline. However, integrati ...
Springer Verlag2015Integrated biosensors for cell culture monitoring
Giovanni De Micheli, Sandro Carrara, Jacopo Olivo, Cristina Boero
Biosensors for endogenous compounds, such as glucose and lactate, are applied to monitor cell cultures. Cells can be cultivated for several purposes, such as understanding and modeling some biological mechanisms, the development of new drugs and therapies, ...
2014