Publication

Privacy-Enhancing Technologies for Medical and Genomic Data: From Theory to Practice

Publications associées (135)

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Development of an interactive genome browser to visualize and analyse large scale genomic data

Lucas Sinclair

Genomic bioinformatics is a growing and developing field. Indeed, data analysis is becoming an integrative and essential part of any quantitative biological experiment as the technologies evolve and the wet lab methods used generate larger and larger quant ...

2010

P450-mediated electrochemical sensing of drugs in human plasma for personalized therapy

Giovanni De Micheli, Sandro Carrara, Andrea Cavallini

Nowadays, the concept of personalized therapy gains momentum. Pharmacogenomics, which represents a first answer to these needs, has the drawback of neglecting some variations of therapy response due to non-genetic factors. The aim of this paper is to inves ...

2010

Inversion-based genomic signatures

Bernard Moret, Krister Swenson

Background: Reconstructing complete ancestral genomes (at least in terms of their gene inventory and arrangement) is attracting much interest due to the rapidly increasing availability of whole genome sequences. While modest successes have been reported fo ...

2009

The Microbe browser for comparative genomics

Jacques Rougemont, Alexandre Gattiker, Marco Pagni, Ioannis Xenarios

The Microbe browser is a web server providing comparative microbial genomics data. It offers comprehensive, integrated data from GenBank, RefSeq, UniProt, InterPro, Gene Ontology and the Orthologs Matrix Project (OMA) database, displayed along with gene pr ...

Oxford University Press2009

Data-centric trust in ephemeral networks

Maxime Raya

New network types require new security concepts. Surprisingly, trust – the ultimate goal of security – has not evolved as much as other concepts. In particular, the traditional notion of building trust in entities seems inadequate in an ephemeral environme ...

EPFL2009

Bacterial strategies to overcome insect defences

Bruno Lemaitre

Recent genetic and molecular analyses have revealed how several strategies enable bacteria to persist and overcome insect immune defences. Genetic and genomic tools that can be used with Drosophila melanogaster have enabled the characterization of the path ...

2008

Circuits and Systems for High-Throughput Biology

Giovanni De Micheli, Luca Benini

The beginning of this millennium has been marked by some remarkable scientific events, notably the completion of the first objective of the Human Genome Project [HGP], i.e., the decoding of the 3 billion bases that compose the human genome. This success ha ...

2006

Controlled and localized genetic manipulation in the brain

Carl Petersen, Rachel Aronoff

Brain structure and function are determined in part through experience and in part through our inherited genes. A powerful approach for unravelling the balance between activity-dependent neuronal plasticity and genetic programs is to directly manipulate th ...

2006

Similarities and differences of polyadenylation signals in human and fly

Felix Naef, Philipp Bucher

ABSTRACT: BACKGROUND: Cleavage of messenger RNA (mRNA) precursors is an essential step in mRNA maturation. The signal recognized by the cleavage enzyme complex has been characterized as an A rich region upstream of the cleavage site containing a motif with ...

2006

The Security and Privacy of Smart Vehicles

Jean-Pierre Hubaux, Jun Luo, Srdan Capkun

Road safety, traffic management, and driver convenience continue to improve, in large part thanks to appropriate usage of information technology. But this evolution has deep implications for security and privacy, which the research community has overlooked ...

2004