Ten years of biophotonics single-photon SPAD imager applications: retrospective and outlook, Multiphoton Microscopy in the Biomedical Sciences XVII
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Future digital signal processing (DSP) systems must provide robustness on algorithm and application level to the presence of reliability issues that come along with corresponding implementations in modern semiconductor process technologies. In this paper, ...
The advent of single-photon detectors known as Single-Photon Avalanche Diodes in standard CMOS technology opened the way to new perspectives in integrating these ultra sensitive light sensors with digital logic. Light has some interesting properties that a ...
Imaging techniques based on time-correlated single photon counting (TCSPC), such as fluorescence lifetime imaging microscopy (FLIM), rely on fast single-photon detectors as well as timing electronics in the form of time-to-digital or time-to-analog convert ...
Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2010
Microfluidics plays a key role in the design of automated platforms for realizing biological assays in a miniaturized format. Several advantages are offered by a microfluidic system, namely, low sample and reagent consumption (typically a few microliters), ...
Digital IC designers often use SRAM macrocells to implement on-chip memory functionality. In this paper we argue that in several situations, standard cell based memories (SCMs) can have advantages over SRAM macrocells. Various ways to implement SCMs are pr ...
The invention of the integrated circuit and the manufacturing progress as well as continuing progress in the manufacturing process are the fundamental engines for the implementation of all technologies that support today's information society. The vast maj ...
Detection of scintillation light from LSO (Lutetiumoxyorthosilicate) crystals used in positron emission tomography (PET) is traditionally based on photo- multipliers. The proposal is to develop a novel photo- sensor, which is based on vertically integratin ...
As dictated by ongoing technology scaling and the advent of multi-core systems, each new generation of microprocessors and digital signal processors provides higher computing power and data throughput. However, the available bandwidth of the input/output ( ...
Several physical quantities of interest are of quantum nature, often measurable as distinct particles. Light is one such example, photons being its particles. In conventional detectors, light is converted onto electrical charges and hence onto a current or ...
We report the development of piezoresistive cantilevers for intermolecular force detection in biochemical sensing, by using a commercial CMOS technology. The detection of the small forces involved in molecular recognition requires cantilevers with a small ...