Publication
Photothermal Off-Resonance Tapping for Rapid and Gentle Atomic Force Imaging of Live Cells
Publications associées (49)
Detecting the metabolism of individual yeast mutant strain cells when aged, stressed or treated with antioxidants with diamond magnetometry
Free radicals play a key role in the ageing process. However, free radicals are small, reactive and short lived and thus challenging to measure. We utilize a new technique called diamond magnetometry for this pur-pose. We make use of nitrogen vacancy cente ...
ELSEVIER SCI LTD2023Live-seq enables temporal transcriptomic recording of single cells
Bart Deplancke, Vincent Roland Julien Gardeux, Orane Josiane Guillaume-Gentil, Riccardo Dainese, Wanze Chen, Pernille Yde Rainer, Magda Zachara, Wouter Saelens
Single-cell transcriptomics (scRNA-seq) has greatly advanced our ability to characterize cellular heterogeneity(1). However, scRNA-seq requires lysing cells, which impedes further molecular or functional analyses on the same cells. Here, we established Liv ...
NATURE PORTFOLIO2022Optical microscopy gets down to angstroms
Suliana Manley, Giorgio Tortarolo
Super-resolution microscopy at angstrom precision could pave the way to optical structural biology in cells. ...
NATURE PORTFOLIO2022The influence of the crowding assumptions in biofilm simulations
Vassily Hatzimanikatis, Liliana Angeles Martinez
Author summary In nature, many organisms grow in crowded biofilms that protect against stressful conditions, making their control/eradication a challenge. Modeling these microbial systems is a valuable tool for studying the interactions among cells and exp ...
PUBLIC LIBRARY SCIENCE2021Bistable Auxetic Surface Structures
Mark Pauly, Tian Chen, Max Schnaubelt
We present Bistable Auxetic Surface Structures, a novel deployable material system based on optimized bistable auxetic cells. Such a structure can be flat-fabricated from elastic sheet material, then deployed towards a desired double-curved target shape by ...
ASSOC COMPUTING MACHINERY2021Nanomechanical bio-sensing for fast and reliable detection of viability and susceptibility of microorganisms
Giovanni Dietler, Sandor Kasas, María Inés Villalba, Leonardo Venturelli, Raphaël Foschia
The metabolic activity of living organisms results in cellular motion on a nanometric scale that can be efficiently detected by micro- and nano- fabricated sensors. Quartz crystal microbalance and atomic force microscopy (AFM) inspired techniques have rece ...
2021Tweaking DNA of myeloid cells curbs cancer spread
Blood cells called myeloid cells can facilitate metastasis - the spread of a tumour to distant organs. Taming these cells with drugs that alter the chemical structure of their DNA limits metastasis in mice. ...
NATURE PUBLISHING GROUP2020Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms
Mélanie Thérèse Marie Hannebelle
Mycobacterium tuberculosis, the etiological agent for the tuberculosis disease, is a bacterial pathogen thought to infect about a quarter of the global human population. It is the first cause of death among infectious diseases, and is most prevalent in low ...
EPFL2020Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry
Olaia Maria Naveiras Torres-Quiroga, George Coukos, Mukul Girotra, Nicola Vannini, Alexandre Harari
A fine balance of quiescence, self-renewal, and differentiation is key to preserve the hematopoietic stem cell (HSC) pool and maintain lifelong production of all mature blood cells. In recent years cellular metabolism has emerged as a crucial regulator of ...
2019Overlapping and essential roles for molecular and mechanical mechanisms in mycobacterial cell division
Georg Fantner, John McKinney, Adrian Pascal Nievergelt, Pascal Damian Odermatt, Haig Alexander Eskandarian, Mélanie Thérèse Marie Hannebelle
Mechanisms to control cell division are essential for cell proliferation and survival. Bacterial cell growth and division require the coordinated activity of peptidoglycan synthases and hydrolytic enzymes to maintain mechanical integrity of the cell wall. ...
2019