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Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution
Publications associées (36)
Fabrication of micrometer-sized drops as templates for particles
Drops are omnipresent in our daily life for example in the form of rain drops or as oil drops in a salad dressing. On a technological basis, drops can be used to conduct chemical or biological reactions. These drops often serve as templates to produce mate ...
EPFL2021Characterizing crystalline defects in single nanoparticles from angular correlations of single-shot diffracted X-rays
Christoph Bostedt, Alessandro Colombo, Giorgio Rossi
Characterizing and controlling the uniformity of nanoparticles is crucial for their application in science and technology because crystalline defects in the nanoparticles strongly affect their unique properties. Recently, ultra-short and ultra-bright X-ray ...
INT UNION CRYSTALLOGRAPHY2020Refinement for single-nanoparticle structure determination from low-quality single-shot coherent diffraction data
Christoph Bostedt, Christophe Nicolas
With the emergence of X-ray free-electron lasers, it is possible to investigate the structure of nanoscale samples by employing coherent diffractive imaging in the X-ray spectral regime. In this work, we developed a refinement method for structure reconstr ...
INT UNION CRYSTALLOGRAPHY2020Spatio-temporal shaping of a free-electron wave function via coherent light-electron interaction
Fabrizio Carbone, Giovanni Maria Vanacore, Ivan Madan
The past decade has witnessed a quantum revolution in the field of computation, communication and materials investigation. A similar revolution is also occurring for free-electron based techniques, where the classical treatment of a free electron as a poin ...
SPRINGERNATURE2020Ultrafine particle concentration measured during the Arctic Ocean 2018 expedition
Julia Schmale, Andrea Baccarini
The ultrafine particle (UFP) concentration is the concentration of particles having a diameter between 2.5 and 15 nm, it is reported in terms of particle number per cubic centimeter at a time resolution of 10 minutes. UFP are the smallest particles within ...
2020Contactless optical trapping and manipulation of nanoparticles utilizing SIBA mechanism and EDL force
On-chip optical tweezers based on evanescent fields overcome the diffraction limit of the free-space optical tweezers and can be a promising technique for developing lab-on-a-chip devices. While such trapping allows for low-cost and precise manipulation, i ...
2019Multispectroscopic Study of Single Xe Clusters Using XFEL Pulses
Christoph Bostedt, Christophe Nicolas
X-ray free-electron lasers (XFELs) deliver ultrashort coherent laser pulses in the X-ray spectral regime, enabling novel investigations into the structure of individual nanoscale samples. In this work, we demonstrate how single-shot small-angle X-ray scatt ...
2019Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution
Using the excellent performances of a SACLA (RIKEN/HARIMA, Japan) X-ray free electron laser (X-FEL), coherent diffraction imaging (CDI) was used to detect individual liposome particles in water, with or without inserted doxorubicin nanorods. This was possi ...
2018Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene
Here we present a new approach to diffraction imaging of amyloid fibrils, combining a freestanding graphene support and single nanofocused X-ray pulses of femtosecond duration from an X-ray free-electron laser. Due to the very low background scattering fro ...
Springer Science and Business Media LLC2018Generation and measurement of sub-micrometer relativistic electron beams
Rasmus Ischebeck, Eugenio Ferrari, Christian David
The generation of low-emittance electron beams has received significant interest in recent years. Driven by the requirements of X-ray-free electron lasers, the emittance of photocathode injectors has been reduced significantly, with corresponding increase ...
NATURE PUBLISHING GROUP2018