An ecotoxicological view on neurotoxicity assessment
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This thesis proposes some contributions to the spatial modelling of species distributions and extreme values. Predictive models are increasingly used to model the distribution of species and to estimate the potential effects of global change on biodiversit ...
Disentangling the mechanisms mediating the coexistence of habitat specialists and generalists has been a long-standing subject of investigation. However, the roles of species traits and environmental and spatial factors have not been assessed in a unifying ...
Plant community composition is recognized more and more for playing an important role in ecosystem processes, such as C cycling. In particular, plant functional type (PFT) composition seems to have a key regulatory role, yet the underlying mechanisms in ...
The risk posed by complex chemical mixtures in the environment to wildlife and humans is increasingly debated, but has been rarely tested under environmentally relevant scenarios. To address this issue, two mixtures of 14 or 19 substances of concern (pesti ...
We present novel analytical results concerning ecosystem species diversity that stem from a proposed coarse-grained neutral model based on birth-death processes. The relevance of the problem lies in the urgency for understanding and synthesizing both theor ...
We present new theoretical and empirical results on the probability distributions of species persistence times in natural ecosystems. Persistence times, defined as the timespans occurring between species' colonization and local extinction in a given geogra ...
Protocols for evaluating chemical toxicity at the cellular level using fish cell lines are described in this unit. Routine methodologies for growing salmonid cell lines, and using them in aquatic toxicology studies that support the mandate of the Organizat ...
Background The Cefic Mixtures Industry Ad-hoc Team (MIAT) has investigated how risks from combined exposures can be effectively identified and managed using concepts proposed in recent regulatory guidance, new advances in risk assessment, and lessons learn ...
2012
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It is now well recognized that the surfaces of nanoparticles (NPs) are coated with biomolecules (e. g., proteins) in a biological medium. Although extensive reports have been published on the protein corona at the surface of NPs in vitro, there are very fe ...
Royal Soc Chemistry2014
The risk of chemical mixtures to ecosystems is often assessed by applying the model of concentration addition or response addition combined with species sensitivity distribution (SSD) curves. Mixture effect predictions have been shown to be consistent only ...
Society of Environmental Toxicology and Chemistry Press2013
