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An ecotoxicological view on neurotoxicity assessment

Related publications (44)

Plant functional diversity drives niche-size-structure of dominant microbial consumers along a poor to extremely rich fen gradient

Vincent Eric Jules Jassey, Mariusz Lamentowicz, Bjorn Jozef Maria Robroek

Plant community composition is recognized more and more for playing an important role in ecosystem processes, such as C cycling. In particular, plant functional type (PFT) composition seems to have a key regulatory role, yet the underlying mechanisms in ...

Wiley-Blackwell2014

Contributions to Spatial Statistics

Emeric Rolland Georges Thibaud

This thesis proposes some contributions to the spatial modelling of species distributions and extreme values. Predictive models are increasingly used to model the distribution of species and to estimate the potential effects of global change on biodiversit ...

EPFL2014

Coexistence of specialist and generalist species is shaped by dispersal and environmental factors

Séverine Vuilleumier Varisco

Disentangling the mechanisms mediating the coexistence of habitat specialists and generalists has been a long-standing subject of investigation. However, the roles of species traits and environmental and spatial factors have not been assessed in a unifying ...

2014

Mixtures of Chemical Pollutants at European Legislation Safety Concentrations: How Safe Are They?

Kristin Schirmer

The risk posed by complex chemical mixtures in the environment to wildlife and humans is increasingly debated, but has been rarely tested under environmentally relevant scenarios. To address this issue, two mixtures of 14 or 19 substances of concern (pesti ...

Oxford University Press2014

Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats

Heinrich Hofmann, Marie-Gabrielle Chantal Brigitte Ollivier Beuzelin, Lionel André Maurizi, Morteza Mahmoudi, Usawadee Sakulkhu

It is now well recognized that the surfaces of nanoparticles (NPs) are coated with biomolecules (e. g., proteins) in a biological medium. Although extensive reports have been published on the protein corona at the surface of NPs in vitro, there are very fe ...

Royal Soc Chemistry2014

Critical issues in using the common mixture toxicity models concentration addition or response addition on species sensitivity distributions: A theoretical approach

Vincent Gregorio

The risk of chemical mixtures to ecosystems is often assessed by applying the model of concentration addition or response addition combined with species sensitivity distribution (SSD) curves. Mixture effect predictions have been shown to be consistent only ...

Society of Environmental Toxicology and Chemistry Press2013

The use of fish-derived cell lines for investigation of environmental contaminants: an update following OECD’s fish toxicity testing framework No. 171.

Kristin Schirmer

Protocols for evaluating chemical toxicity at the cellular level using fish cell lines are described in this unit. Routine methodologies for growing salmonid cell lines, and using them in aquatic toxicology studies that support the mandate of the Organizat ...

wileyonlinelibrary.com2013

An exactly solvable coarse-grained model for species diversity

Andrea Rinaldo, Samir Suweis, Amos Maritan

We present novel analytical results concerning ecosystem species diversity that stem from a proposed coarse-grained neutral model based on birth-death processes. The relevance of the problem lies in the urgency for understanding and synthesizing both theor ...

Iop Publishing Ltd2012

On species persistence-time distributions

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Samir Suweis, Amos Maritan

We present new theoretical and empirical results on the probability distributions of species persistence times in natural ecosystems. Persistence times, defined as the timespans occurring between species' colonization and local extinction in a given geogra ...

Elsevier2012

A decision tree for assessing effects from exposures to multiple substances

Xiaoxue Han

Background The Cefic Mixtures Industry Ad-hoc Team (MIAT) has investigated how risks from combined exposures can be effectively identified and managed using concepts proposed in recent regulatory guidance, new advances in risk assessment, and lessons learn ...

2012

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