Integrated elastomer-based device for measuring the mechanics of adherent cell monolayers
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One of the great challenges in microscale science and engineering is the independent manipulation of cells and man-made objects on the micron scale. For such work, motile microorganisms are integrated with engineered systems to construct microbiorobots (MB ...
We present a new generation of piezoresistive nanomechanical Membrane-type Surface stress Sensor(MSS) chips, which consist of a two dimensional array of MSS on a single chip. The implementation of several optimization techniques in the design and microfabr ...
cells is achieved with randomly textured superstrates (TCO and/or glass). Due to a continuous and broad variation of occurring structure sizes in such textures, their optical simulation is challenging. In this paper we introduce an approach to establish a ...
Although canonical Notch signaling regulates multiple hematopoietic lineage decisions including T cell and marginal zone B cell fate specification, the downstream molecular mediators of Notch function are largely unknown. We showed here that conditional in ...
In this paper, the development of a low temperature bonding process focused on indium-based technology for microfabricated alkali cells is presented. The intended application is the use of these cells in chip scale atomic clocks. The existing technology is ...
Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...
The increase of bacterial resistance against various disinfection processes is a worrying phenomenon. As a consequence, the search for alternative techniques for fighting micro-organisms has become one of the major issues of these last few years. In this d ...
We present a new type of microinstrument allowing manipulation and mechanical perturbation of individual cells under an optical microscope. These instruments, which we call microplates, are pulled from rectangular glass bars. They have flat tips, typically ...
In this contribution we present the development of three microfabricated devices for the study of neuronal and cellular networks. Together, these devices form an attractive toolbox, which is useful to stimulate and record signals of both electrical and che ...
The invention relates to a device for dispensing droplets comprising a first channel (8, 10), known as the main channel, for circulating a first liquid flow, a second channel (12, 13) for circulating fluid, forming an intersection area (27) with the first ...