Publications associées à Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

Sex differentiation in grayling (Salmonidae) goes through an all-male stage and is delayed in genetic males who instead grow faster

Oliver Michele Selmoni

Fish populations can be threatened by distorted sex ratios that arise during sex differentiation. Here we describe sex differentiation in a wild grayling (Thymallus thymallus) population that suffers from distorted sex ratios. We verified that sex determin ...

Springer Nature2017

Integrated field, laboratory, and theoretical study of PKD spread in a Swiss prealpine river

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Luca Carraro, Marino Gatto

Proliferative kidney disease (PKD) is a major threat to wild and farmed salmonid populations because of its lethal effect at high water temperatures. Its causative agent, the myxozoan Tetracapsuloides bryosalmonae, has a complex lifecycle exploiting freshw ...

National Academy of Sciences2017

A novel two-compartment barrier model for investigating nanoparticle transport in fish intestinal epithelial cells

Kristin Schirmer, Laura Sigg

We introduce a novel in vitro rainbow trout intestinal barrier model and demonstrate its suitability for investigating nanoparticle transport across the intestinal epithelium. Rainbow trout (Oncorhynchus mykiss) intestinal cells (RTgutGC) were grown as mon ...

Royal Soc Chemistry2016

Effect of media composition on bioavailability and toxicity of silver and silver nanoparticles in fish intestinal cells (RTgutGC)

Kristin Schirmer

To understand conditions affecting bioavailability and toxicity of citrate-coated silver nanoparticles (cit-AgNP) and dissolved silver at the luminal enterocyte interface, we exposed rainbow trout (Oncorhynchus mykiss) gut cells (RTgutGC) in media of contr ...

Taylor & Francis Ltd2016

Toxicity of silver nanoparticles to a fish gill cell line: Role of medium composition

Kristin Schirmer, Laura Sigg, Renata Behra, Yang Yue

In aqueous solutions, silver nanoparticle (AgNP) behavior is affected by a variety of factors which lead to altered AgNP size and toxicity. Our research aims to explore the effect of media composition on citrate-coated AgNP (cit-AgNP) behavior and toxicity ...

Informa Healthcare2015

Microfluidic chip for monitoring Ca2+ transport through a confluent layer of intestinal cells

Martinus Gijs, Paolo Silacci, Hüseyin Cumhur Tekin, Josias Basil Wacker, Christine Ruffert, Guy Vergères

The absorption of dietary calcium through the intestinal barrier is essential for maintaining health in general and especially of the bone system. We propose a microfluidic model that studies free calcium (Ca2+) transport through a confluent monolayer of C ...

Royal Soc Chemistry2014

Attractiveness of a lateral shelter in a channel as a refuge for juvenile brown trout during hydropeaking

Anton Schleiss, Jean-Marc Ribi, Armin Julius Peter

Peak power production in hydroelectric storage power plants results in frequent and intense flow variations in the rivers downstream of the plants. Fish populations can be negatively impacted when subjected to these so-called hydropeaking phenomena. In res ...

Springer Verlag2014

Measured and Modeled Toxicokinetics in Cultured Fish Cells and Application to In Vitro - In Vivo Toxicity Extrapolation

Kristin Schirmer, Julita Maria Stadnicka-Michalak

Effect concentrations in the toxicity assessment of chemicals with fish and fish cells are generally based on external exposure concentrations. External concentrations as dose metrics, may, however, hamper interpretation and extrapolation of toxicological ...

Public Library Science2014

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Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

Sex differentiation in grayling (Salmonidae) goes through an all-male stage and is delayed in genetic males who instead grow faster

Integrated field, laboratory, and theoretical study of PKD spread in a Swiss prealpine river

A novel two-compartment barrier model for investigating nanoparticle transport in fish intestinal epithelial cells

Effect of media composition on bioavailability and toxicity of silver and silver nanoparticles in fish intestinal cells (RTgutGC)

Toxicity of silver nanoparticles to a fish gill cell line: Role of medium composition

Microfluidic chip for monitoring Ca2+ transport through a confluent layer of intestinal cells

Attractiveness of a lateral shelter in a channel as a refuge for juvenile brown trout during hydropeaking

PPAR beta/delta activation of CD300a controls intestinal immunity

Measured and Modeled Toxicokinetics in Cultured Fish Cells and Application to In Vitro - In Vivo Toxicity Extrapolation

Investigating Alternatives To The Fish Early-Life Stage Test: A Strategy For Discovering And Annotating Adverse Outcome Pathways For Early Fish Development

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Chattez avec Graph Search

A novel two-compartment barrier model for investigating nanoparticle transport in fish intestinal epithelial cells

Effect of media composition on bioavailability and toxicity of silver and silver nanoparticles in fish intestinal cells (RTgutGC)

Integrated field, laboratory, and theoretical study of PKD spread in a Swiss prealpine river

Sex differentiation in grayling (Salmonidae) goes through an all-male stage and is delayed in genetic males who instead grow faster

Investigating Alternatives To The Fish Early-Life Stage Test: A Strategy For Discovering And Annotating Adverse Outcome Pathways For Early Fish Development

Toxicity of silver nanoparticles to a fish gill cell line: Role of medium composition

Attractiveness of a lateral shelter in a channel as a refuge for juvenile brown trout during hydropeaking

Measured and Modeled Toxicokinetics in Cultured Fish Cells and Application to In Vitro - In Vivo Toxicity Extrapolation

Microfluidic chip for monitoring Ca2+ transport through a confluent layer of intestinal cells

PPAR beta/delta activation of CD300a controls intestinal immunity