Publication
Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery
Publications associées (16)
Automatic Mallampati Classification Using Active Appearance Models
Jean-Philippe Thiran, Matteo Sorci, Anil Yuce, Gabriel Louis Cuendet
Difficult tracheal intubation assessment is an important research topic in anesthesia as failed intubations are important causes of mortality in anesthetic practice. The modified Mallampati score is widely used, alone or in conjunction with other criteria, ...
2012X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
General anaesthetics have enjoyed long and widespread use but their molecular mechanism of action remains poorly understood. There is good evidence that their principal targets are pentameric ligand-gated ion channels (pLGICs) such as inhibitory GABA(A) (γ ...
Nature Publishing Group2011Deep thiopental anesthesia alters steady-state glucose homeostasis but not the neurochemical profile of rat cortex
Barbiturates are regularly used as an anesthetic for animal experimentation and clinical procedures and are frequently provided with solubilizing compounds, such as ethanol and propylene glycol, which have been reported to affect brain function and, in the ...
Wiley-Blackwell2010Modeling the effects of midazolam on cortical and thalamic neurons
Controversy exists regarding the site where anesthetics act in the brain to produce sedation and unconsciousness. Actions in the cerebral cortex and thalamus are likely, although the relative importance of each site is unclear. We used in computo modeling ...
2009Modeling the Gabaergic Action of Etomidate on the Thalamocortical System
BACKGROUND: We have used a computational model of the thalamocortical system to investigate the effects of a GABAergic anesthetic (etomidate) on cerebral cortical and thalamic neuronal function. We examined the effects of phasic an tonic inhibition, as wel ...
2009Estimation of the depth of anaesthesia from interacting physiological oscillators
Nowadays, physiological monitoring is imperative for the safety of medical operations. However, systems which monitor the depth of anaesthesia are still far from reliable, such that still some patients may experience the trauma of remaining conscious under ...
EPFL2008